| Cat. No. |
Product Name |
Information |
| PC-62825 |
CCG-203971
Rho/MKL1/SRF inhibitor
|
CCG-203971(CCG203971) is a potent Rho/MKL1/SRF transcriptional pathway inhibitor, suppresses PC-3 cell migration in scratch wound assays (IC50=4.2 uM), blocks nuclear localization and activity of MRTF-A in SK-Mel-147 cells. |
| PC-62824 |
CCG-232601
MRTF/SRF inhibitor
|
CCG-232601 is a potent (IC50=0.55 uM), orally bioavailable inhibitor of Rho/MRTF/SRF transcriptional pathway that target transcriptional factor MRTF. |
| PC-62786 |
VU6001221
Choline transporter inhibitor
|
VU6001221 is a potent choline transporter (CHT) inhibitor with IC50 of 270 nM. |
| PC-62785 |
ML352
Choline transporter inhibitor
|
ML352 (VU0476201) is a potent, selective choline transporter (CHT) inhibitor with Ki of 92 nM. |
| PC-62753 |
Sepin-1
Separase inhibitor
|
Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM. |
| PC-62745 |
DB2115
PU.1 inhibitor
|
DB2115 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 1.0 nM. |
| PC-62744 |
DB2313
PU.1 inhibitor
|
DB2313 is a small-molecule transcription factor PU.1 inhibitor abrogating DNA binding by PU.1 with Kd of 29 nM. |
| PC-62713 |
S1P lyase inhibitor 28
S1P lyase inhibitor
|
S1PL-IN-28 (S1P lyase inhibitor 28) is a novel S1P lyase inhibitor with in vitro IC50 of 120 nM, cell IC50 of 230 nM. |
| PC-62693 |
SLC25A20-IN-21
SLC25A20 inhibitor
|
SLC25A20-IN-21 is a SLC25A20 ligand that increases long-chain (>C14) acylcarnitine content and reduces maximal exogenous fatty acid oxidation in HSC-5 cells. |
| PC-62692 |
PTGR2 inhibitor 22
PTGR2 inhibitor
|
PTGR2-IN-22 (PTGR2 inhibitor 22) is a potent PTGR2 (prostaglandin reductase 2) ligand that inhibits 15-keto-PGE2 reductase activity with IC50 of 0.55 uM in HEK293T cells. |
| PC-62689 |
Brequinar
DHODH inhibitor
|
Brequinar (DuP785, NSC 368390) is a potent and selective inhibitor of DHODH with IC50 of 20 nM, triggers differentiation in the ER-HoxA9, U937, and THP1 cells with an ED50 of 1 uM. |
| PC-62688 |
Perhexiline maleate
CPT1/CPT2 inhibitor
|
Perhexiline maleate (WSM 3978G) is a prophylactic antianginal agent that inhibits carnitine palmitoyltransferase (CPT1/CPT2). |
