| Cat. No. |
Product Name |
Information |
| PC-20012 |
GCN2iB
GCN2 inhibitor
|
GCN2iB (GCN2 inhibitor) is a potent, selective and ATP-competitive GCN2 inhibitor with IC50 of 2.4 nM. |
| PC-49858 |
Tafamidis
Transthyretin stabilizer
|
Tafamidis is a potent and selective transthyretin (TTR) kinetic stabilizer with EC50 of 2.7-3.2 uM for WT-TTR and mutant tetramers V30M-TTR, V122I-TTR, inhibits amyloidogenesis. |
| PC-49857 |
AG10
Transthyretin stabilizer
|
AG10 is a potent and selective kinetic stabilizer and ligand of transthyretin (TTR) ligand with apparent binding constant (Kapp) of 193 nM for WT-TTR. |
| PC-49851 |
Nalacin
group II GH3 inhibitor
|
Nalacina is a small molecule that partially mimicks the effects of auxin and potent inhibitor of indole-3-acetic acid (IAA) conjugation mediated by group II GH3 (Gretchen Hagen 3) in vascular plants, inhibits Gretchen Hagen 3 (GH3) acyl acid amido synthetases. |
| PC-49847 |
EP055
Sperm EPPIN inhibitor
|
EP055 (EP-055) is a small molecule that targets EPPIN on the surface of sperm and inhibits motility (IC50=199.5 uM, CASA assay using human sperm), binds to the C-terminal domain of EPPIN. |
| PC-49819 |
EG-011
WASP activator
|
EG-011 (WASP activator EG-011, EG011) is a first-in-class, small molecule activator of the auto-inhibited form of Wiskott-Aldrich syndrome protein (WASp) with selective anti-tumor activity in lymphomas. |
| PC-49816 |
SS-1-148
hOAT inhibitor
|
SS-1-148 is a potent, selective inhibitor of human ornithine δ-aminotransferase (hOAT) with Ki of 60 uM, shows excellent selectivity over other related aminotransferases (e.g., GABA-AT). |
| PC-49815 |
OV329
GABA-AT inhibitor
|
OV329 (OV 329) is a highly potent inactivator of gamma-aminobutyric acid aminotransferase (GABA-AT) with Ki of 9.69 uM. |
| PC-49807 |
Muramyl Dipeptide
|
Muramyl Dipeptide is a naturally occurring component of bacterial cell walls that has the capacity to activate macrophages, is an immunological adjuvant. |
| PC-49803 |
ClpP agonist TR-65
|
ClpP agonist TR-65 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.3 nM. |
| PC-49802 |
ClpP agonist TR-57
|
ClpP agonist TR-57 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 15.5 nM. |
| PC-49801 |
ClpP agonist TR-27
|
ClpP agonist TR-27 is a potent small molecule agonist of mitochondrial ClpP protease with KD value of 23.7 nM. |
