Catalog No.: PC-63111Not For Human Use, Lab Use Only.
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.
CE3F4 is a potent, noncompetitive EPAC1 inhibitor that blocks EPAC1-induced Rap1 activation both in cell-free systems and in intact cells and did not influence protein kinase A holoenzyme activity.
CE3F4 reduces the exchange activity of Epac1 induced by 007 (2 uM) with IC50 of 23 uM.
CE3F4 is a useful pharmacological tools for determining the biological functions of EPAC1 in a wide range of biological processes.
