| Cat. No. |
Product Name |
Information |
| PC-61677 |
ATN-224
SOD1 inhibitor
|
ATN-224 (Choline tetrathiomolybdate, WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects. |
| PC-61674 |
SBI-993
MondoA inhibitor
|
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability. |
| PC-61673 |
SBI-477
MondoA inhibitor
|
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively. |
| PC-61554 |
NCGC00185684
|
NCGC00185684 (ML154) is a potent, selective, brain penetrant NPSR (Neuropeptide S receptor. |
| PC-61485 |
VJ115
ENOX1 inhibitor
|
VJ115 (VJ-115) is a small molecule inhibitor of NADH oxidase ENOX1 with IC50 of 10 uM, increases intracellular NADH in endothelial cells and inhibits endothelial cell tubule formation. |
| PC-61473 |
BI 1467335
|
BI 1467335 (PXS-4728A, PXS-4728) is a potent, selective, orally active SSAO/VAP-1 (AOC3) inhibitor with IC50 of 5 nM. |
| PC-61463 |
VPC-18005
|
VPC-18005 (VPC18005) is a novel small molecule ERG (ETS-related gene) antagonist that inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain, disrupts the ERG binding to DNA (Kd=250 uM). |
| PC-61428 |
Ibiglustat
|
Ibiglustat (Venglustat, Genz-682452) is an orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access. |
| PC-61427 |
EXEL-0346
GCS inhibitor
|
EXEL-0346 (EXEL0346) is a novel potent, orally active Glucosylceramide synthase (GCS) inhibitor with IC50 of 2 nM. |
| PC-61423 |
Myriocin
|
Myriocin (ISP-1) is an amino fatty acid antibiotic that is 10- to 100-fold more potent than cyclosporin A as an immunosuppressive agent of the immune response in vitro and in vivo. |
| PC-61399 |
Setafrastat
|
Setafrastat is a small molecule hair growth stimulator. |
| PC-61393 |
Parimifasor
ATPase modulator
|
Parimifasor (LYC-30937-EC, LYC30937) is an orally bioavailable, enteric-coated ATPase modulator as a gut-directed therapy for the treatment of inflammatory bowel disease (IBD). |
