TLX agonist 10

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Chemical Structure : TLX agonist 10

Catalog No.: PC-72812Not For Human Use, Lab Use Only.

TLX agonist 10 is potent, selective agonist of the orphan nuclear receptor tailless homologue (TLX, NR2E1) with pEC50 of 6.6.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

TLX agonist 10 is potent, selective agonist of the orphan nuclear receptor tailless homologue (TLX, NR2E1) with pEC50 of 6.6.
TLX agonist 10 is a valuable TLX agonist tool with submicromolar potency and high selectivity over related nuclear receptors, rendering it suitable for functional studies on TLX.

Physicochemical Properties

M.Wt	468.480
Formula	C25H23F3N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-butoxy-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)quinoline-4-carboxamide

References

1. Giuseppe Faudone, et al. J Med Chem. 2022 Jan 6. doi: 10.1021/acs.jmedchem.1c01757.

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TLX agonist 10

Biological Activity

Physicochemical Properties

References

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