| Cat. No. |
Product Name |
Information |
| PC-45514 |
BoNT-IN-1
BoNT inhibitor
|
BoNT-IN-1 is a potent inhibitor of Botulinum Neurotoxin A (BoNT) Light Chain with IC50 of 0.9 uM. |
| PC-45318 |
Amicarbazone
Photosystem II Inhibitor
|
Amicarbazone (BAY-314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII). |
| PC-45038 |
ISO-1
MIF inhibitor
|
ISO-1 is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with IC50 of 7 uM. |
| PC-42227 |
ML390
DHODH inhibitor
|
ML390 is a potent DHODH inhibitor that causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) AML models (ED50=2 uM). |
| PC-42253 |
HTHQ
Anti-oxidative agent
|
HTHQ is a potent anti-oxidative agent that effectively scavenges t-butyl peroxyl radicals with IC50 of 0.31 mM (ROS inhibition). |
| PC-44643 |
HJC0350
EPAC2 antagonist
|
HJC0350 is a potent and specific EPAC2 antagonist with IC50 of 0.3 uM for competing with 8-NBD-cAMP in binding EPAC2, about 133-fold more potent than cAMP. |
| PC-42382 |
NIH-12848
PI5P4Kγ inhibitor
|
NIH-12848 is a potent and selective PI5P4Kγ inhibitor with IC50 of 1 uM, shows no significant inhibitory activity for PI5P4Kα and PI5P4Kβ (>100 uM). |
| PC-45393 |
Acebilustat
LTA4H inhibitor
|
Acebilustat (CTX-4430, EP-501) is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor with IC50 of 64 nM for inhibition of LTB4 production in human whole blood. |
| PC-45593 |
Adjudin
|
Adjudin (AF-2364) is a potent analog of lonidamine known to disrupt germ cell adhesion, a potential candidate for male contraceptive development. |
| PC-45493 |
Ro 48-8071 fumarate
2,3-oxidosqualene cyclase inhibitor
|
Ro 48-8071 fumarate is a potent 2,3-oxidosqualene cyclase (OSC) inhibitor with IC50 of 6.5 nM. |
| PC-45492 |
Ro 48-8071
2,3-oxidosqualene cyclase inhibitor
|
Ro 48-8071 is a potent 2,3-oxidosqualene cyclase (OSC) inhibitor with IC50 of 6.5 nM. |
| PC-45095 |
ISA-2011B
PIP5Kα inhibitor
|
ISA-2011B (ISA2011B, ISA 2011B) is a poent, selective inhibitor of Phosphatidylinositol-4-phosphate 5-kinase-α (PIP5Kα). |
