| Cat. No. |
Product Name |
Information |
| PC-47485 |
Neuromedin N
|
A neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.. |
| PC-44669 |
Lucidin
|
Lucidin (NSC 30546) is a mutagenic substance extracted from Rubia tinctorum L., induces DNA repair synthesis in primary rat hepatocytes and transformed C3H/M2-mouse fibroblasts in culture. |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-23451 |
PF-07328948
BDK inhibitor
|
PF-07328948 is the first potent, selective branched-chain ketoacid dehydrogenase kinase (BDK or BCKDK) with in vitro IC50 of 15 nM, and cellular IC50 of 46 nM in human skeletal muscle BDK activity assay. |
| PC-23450 |
UNC10142
CHD1 inhibitor
|
UNC10142 is a first-in-class, specific, cell-active small molecule antagonist of the tandem chromodomains of CHD1 (Chromodomain-Helicase DNA-Binding Protein 1) with binding IC50 of 1.7 uM in TR-FRET assays. |
| PC-23443 |
164A10
Pin1 degrader
|
164A10 is a potent Pin1 destabilizer and degrader with IC50 of 4.1 nM in DELFIA displacement assay, destabilizes Pin1 in vitro and also results more effective in causing Pin1 degradation in cells. |
| PC-23442 |
158H9
Pin1 degrader
|
158H9 is a potent Pin1 destabilizer and degrader with IC50 of 21.5 nM in DELFIA displacement assay, destabilizes Pin1 in vitro and also results more effective in causing Pin1 degradation in cells. |
| PC-23441 |
BJP-07-017-3
Pin1 inhibitor
|
BJP-07-017-3 is a potent, selective, covalent, cell-permeable peptide Pin1 inhibitor (Ki=15 nM), IC50 of 9 nM in DELFIA assays, covalently targets Cys113, a highly conserved cysteine located in the Pin1 active site. |
