| Cat. No. |
Product Name |
Information |
| PC-72022 |
BIM5078
HNF4α antagonist
|
BIM5078 (BIM-5078) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity (EC50=11.9 nM) and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
| PC-72021 |
BI6015
HNF4α antagonist
|
BI6015 (BI-6015) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
| PC-72017 |
INI-60
Kpnβ1 inhibitor
|
INI-60 (Inhibitor of Nuclear Import-60) is a novel small molecule inhibitor of Kpnβ1-mediated nuclear import with anti-cancer activity. |
| PC-72016 |
CNI103
Calcineurin-NFAT inhibitor
|
CNI103 (CNI-103) is a highly potent, cell-permeable, metabolically stable peptidyl inhibitor of Calcineurin-NFAT interaction wioth KD 16 nM and IC50 of 220 nM. |
| PC-72005 |
Reproxalap
RASP inhibitor
|
Reproxalap (ADX-102) is a novel inhibitor of reactive aldehyde species (RASP) for the treatment of ocular inflammation. |
| PC-38334 |
CARD8 activator CQ31
|
CARD8 activator CQ31 is a small molecule that selectively activates CARD8. |
| PC-38326 |
DMT1inhibitor 18a
|
DMT1 inhibitor 18g is the most potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 50 nM in calcein fluorescence assay.. |
| PC-38325 |
DMT1 inhibitor 14a
|
DMT1 inhibitor 14a is a potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 340 nM in calcein fluorescence assay. |
| PC-38324 |
DMT1 inhibitor 6b
|
DMT1 inhibitor 6b is a potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 80 nM in calcein fluorescence assay. |
| PC-38316 |
BNZ132-1
|
BNZ132-1 (QITISILSQINRVFHEKFI) is a specific peptide inhibitor for the IL-2/IL-15 subfamily, directly binds to the γc molecule (CD132). |
| PC-38315 |
BNZ-1
|
BNZ-1 (BNZ132-1-40) is a pegylated peptide, BNZ132-1 conjugated with methoxy-PEG40 maleimide molecule via a specific linker (CGSGG), specifically binds the γc receptor to selectively block IL-2, IL-15 and IL-9 signaling. |
| PC-38216 |
UNC10245092
|
UNC10245092 is a high affinity peptide inhibitor of Calcium and integrin binding protein 1 (CIB1), binds hydrophobic pocket on CIB1 with Kd of 29.4 nM.. |
