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Chemical Structure : Miglustat hydrochloride
CAS No.: 210110-90-0
Catalog No.: PC-45142Not For Human Use, Lab Use Only.
Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase).
Miglustat inhibits glycolipid biosynthesis, has no effect on the maturation of N-linked oligosaccharides or on lysosomal glucocerebrosidase.
Miglustat is used primarily to treat type I Gaucher disease (GD1).
| M.Wt | 255.739 | |
| Formula | C10H22ClNO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
3,4,5-Piperidinetriol, 1-butyl-2-(hydroxymethyl)-, hydrochloride (1:1), (2R,3R,4R,5S)- |
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1. Platt FM, et al. J Biol Chem. 1994 Oct 28;269(43):27108-14.
2. D'Arcangelo G, et al. Neural Plast. 2016;2016:3830424.
3. Fischer PB, et al. J Virol. 1995 Sep;69(9):5791-7.
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