| Cat. No. |
Product Name |
Information |
| PC-20214 |
MIF2 inhibitor 5d
MIF-2 inhibitor
|
MIF2 inhibitor 5d is a selective inhibitor of d-dopachrome tautomerase (d-DT or MIF2) with IC50 of 1.0 μM for MIF2 tautomerase activity and a high selectivity over MIF. |
| PC-20213 |
2,5-pyridinedicarboxylic acid
MIF2 inhibitor
|
2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74. |
| PC-20196 |
ψTnI
cTnI/PKCδ inhibitor
|
ψTnI (Peptide DWRKNIDA) is a selective, high-affinity, eight amino acid peptide inhibitor of cardiac troponin I (cTnI), directly binds to δPKC with high affinity (Kd=5 nM) and inhibits cTnI/δPKC interaction. |
| PC-20166 |
TMX-4084
PIP4K2C binder
|
TMX-4084 (TMX4084) is a highly potent, selective PIP4K2C binder with KD of 7.3 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
| PC-20165 |
TMX-4102
PIP4K2C binder
|
TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
| PC-20158 |
CKi-4
Covalent creatine kinase inhibitor
|
Creatine kinase inhibitor CKi-4 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.3 uM, depletes creatine phosphagen energetics in cells. |
| PC-20157 |
CKi-6
Covalent creatine kinase inhibitor
|
CKi-6 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
| PC-20156 |
(S)-CKi-1
Covalent creatine kinase inhibitor
|
(S)-CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 0.6 uM, depletes creatine phosphagen energetics in cells. |
| PC-20155 |
MitoCKi
Covalent creatine kinase inhibitor
|
MitoCKi (Creatine kinase inhibitor CKi-26) is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 185 nM, depletes creatine phosphagen energetics in cells. |
| PC-20154 |
Creatine kinase inhibitor CKi-1
Covalent creatine kinase inhibitor
|
Creatine kinase inhibitor CKi-1 is a selective, covalent inhibitor of creatine kinases (CKs), inhibits recombinant creatine kinase B (CKB) phosphotransfer activity with IC50 of 1.2 uM, depletes creatine phosphagen energetics in cells. |
| PC-20138 |
SB1501
|
SB1501 (SB 1501) is a bioactive compound that reduces fat accumulation by elevating mitochondrial biogenesis and fatty acid oxidation via the PGC-1α-UCP1 pathway, shows anti-obesity effects in vivo. |
| PC-20118 |
iSB09
ABA receptor agonist
|
iSB09 is a potent, selective small moelcule abscisic acid (ABA) receptor agonist with HAB1 IC50 value of 316 nM (combined with the engineered CsPYL1 ABA receptor CsPYL15m). |
