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Chemical Structure : PSB-KK1415
Catalog No.: PC-21097Not For Human Use, Lab Use Only.
PSB-KK1415 is a selective GPR18 agonist with EC50 of 19.1 nM (hGPR18) in β-arrestin recruitment assays, shows no activity against GPR55.
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PSB-KK1415 is a selective GPR18 agonist with EC50 of 19.1 nM (hGPR18) in β-arrestin recruitment assays, shows no activity against GPR55.
PSB-KK1415 displays >25-fold selectivity versus CB receptors, and shows minimal species differences.
PSB-KK1415 exerts potent anti-inflammatory and anti-nociceptive activities in animal models of intestinal inflammation and inflammatory pain.
| M.Wt | 462.94 | |
| Formula | C24H23ClN6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Fabisiak A, et al. Neurogastroenterol Motil. 2021 Mar;33(3):e14003.
2. Andhika B Mahardhika, et al. J Med Chem. 2024 Jun 17. doi: 10.1021/acs.jmedchem.3c02423.
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