| Cat. No. |
Product Name |
Information |
| PC-22602 |
RNB-61
CB2R agonist
|
RNB-61 is a highly potent, selective and orally bioavailable cannabinoid CB2 receptor (CB2R) full agonist with Ki of 0.57/1.33 nM for hCB2R/mCB2R, >5000-fold selective over hCB1R. |
| PC-22188 |
SR141716
CB1 antagonist
|
Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with Ki of 1.8 nM, no affinity for peripheral cannabinoid receptor. |
| PC-20950 |
AEF0117
CB1 inhibitor
|
AEF0117 (AEF-0117) is a potent, signaling-specific inhibitor of the cannabinoid receptor 1 (CB1), inhibits the decrease in cellular respiration induced by THC (1 µM) in HEK293 cells transfected with hCB1 with IC50 of 3 nM. |
| PC-20746 |
LEI-102
CB2R agonist
|
LEI-102 (LEI 102) is a potent, selective cannabinoid CB2 receptor agonist with binding pKi of 8.0, 1000-fold selectivity over CB1R. |
| PC-20170 |
MRI-1891
CB1R antagonist
|
MRI-1891 (INV-202) is potent, selective, β-Arrestin-2-biased peripheral cannabinoid-1 receptor (CB1R) antagonist with Ki of 0.3 nM (hCB1R), >2000-fold CB1R/CB2R selectivity. |
| PC-20082 |
AM251
CB1 antagonist
|
AM251 (AM 251) is a potent, selective CB1 receptor antagonist (inverse agonist) with IC50 of 8 nM, Ki of 7.49 nM, displays 306-fold selectivity over CB2 receptors. |
| PC-20078 |
URB447
CB1R antagonist
|
URB447 (URB-447) is a peripherally restricted CB(1) antagonist/CB(2) agonist with IC50 of 313 nM (rat CB1) and 41 nM (human CB2). |
| PC-20077 |
AM6545
CB1R antagonist
|
AM6545 (AM-6545) is a potent, selective, oral bioavailable and non-brain-penetrant neutral CB1R antagonist with Ki of 3.3 nM, >100-fold selectivity over CB2R. |
| PC-20051 |
MRL-650
CB1R inhibitor
|
MRL-650 (MRL650) is a potent, selective inverse agonist of CB1 cannabinoid receptor with IC50 of <10 nM. |
| PC-49218 |
S-777469
CB2 agonist
|
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1. |
| PC-47097 |
LY2828360
CB2 agonist
|
LY2828360 is a potent CB2 receptor agonist with similar affinity for human and rat CB2 receptors with Ki of 40.3 nM and 36.7 nM, respectively, shows EC50 of 20.1 nM in [35S]-GTPγS assays. |
| PC-38638 |
JM-00266
CB1 inverse agonist
|
JM-00266 is a novel non-brain penetrant cannabinoid receptor 1 (CB1R) inverse agonist with cAMP EC50 of 248.6 nM in HEK293T/17 cells transfected with murine CB1R. |
