Cat. No. |
Product Name |
Information |
PC-20522 |
Ibipinabant
CB1 antagonist
|
Ibipinabant (SLV319, BMS-646256) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor with Ki of 7.8 nM, >1000-fold selectivity for CB1 over CB2. |
PC-20521 |
PF-514273
CB1 antagonist
|
PF-514273 (PF 514273) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor with Ki of 1.0 nM, >10000-fold selectivity for CB1 over CB2. |
PC-20518 |
JD-5006
CB1 antagonist
|
JD-5006 is a potent, selective and peripherally restricted cannabinoid-1 (CB1) receptor blocker with IC50 of 18 nM, does not inhibit CB2 receptor (IC50>5000 nM). |
PC-20517 |
JD-5037
CB1 antagonist
|
JD-5037 is a potent, selective and peripherally restricted cannabinoid-1 (CB1) receptor blocker with IC50 of 2 nM, does not inhibit CB2 receptor (IC50>1000 nM). |
PC-20082 |
AM251
CB1 antagonist
|
AM251 (AM 251) is a potent, selective CB1 receptor antagonist (inverse agonist) with IC50 of 8 nM, Ki of 7.49 nM, displays 306-fold selectivity over CB2 receptors. |
PC-20078 |
URB447
CB1R antagonist
|
URB447 (URB-447) is a peripherally restricted CB(1) antagonist/CB(2) agonist with IC50 of 313 nM (rat CB1) and 41 nM (human CB2). |
PC-20077 |
AM6545
CB1R antagonist
|
AM6545 (AM-6545) is a potent, selective, oral bioavailable and non-brain-penetrant neutral CB1R antagonist with Ki of 3.3 nM, >100-fold selectivity over CB2R. |
PC-20051 |
MRL-650
CB1R inhibitor
|
MRL-650 (MRL650) is a potent, selective inverse agonist of CB1 cannabinoid receptor with IC50 of <10 nM. |
PC-38638 |
JM-00266
CB1R blocker
|
JM-00266 is a novel non-brain penetrant cannabinoid receptor 1 (CB1R) inverse agonist. |
PC-73457 |
Zevaquenabant
CB1R/iNOS inhibitor
|
Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual CB1 receptor/iNOS inhibitor. |
PC-35625 |
XL-001
|
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM. |
PC-35592 |
AM9405
|
AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist, inhibits the EFS-induced twitch contraction of the ileum and the colon with IC50 of 0.076 and 45.71 nM, respectively. |