| Cat. No. |
Product Name |
Information |
| PC-60757 |
NESS-0327
CB1R antagonist
|
NESS-0327 (NESS0327) is a potent, selective CB1 cannabinoid receptor antagonist with Ki of 350 fM, >60,000-fold selective for the CB1 receptor versus CB2 receptor (Ki=21 nM). |
| PC-60756 |
NESS-040C5
CB2 agonist
|
A potent, reasonably selective cannabinoid CB2 agonist with Ki of 0.4 nM, 25-fold selectivity over CB1 receptor.. |
| PC-60753 |
SR144528
CB2 antagonist
|
SR144528 is a highly potent, selective and orally active antagonist of CB2 receptor with Ki of 0.6 nM. |
| PC-60729 |
AM1241
CB2 agonist
|
AM1241 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 7.1 nM, >80-fold selectivity over CB1 receptors in radioligand binding assay. |
| PC-60728 |
GW405833 hydrochloride
CB2 agonist
|
GW405833 is a potent, selective cannabinoid receptor CB2 agonist with Ki of 3.6 nM, 1200-fold selectivity over CB1. |
| PC-60146 |
Olorinab
CB2 agonist
|
Olorinab (APD371) is a potent, selective and orally available CB2 cannabinoid receptor agonist with EC50 of 6.2 nM. |
| PC-60086 |
AM-6538
|
AM-6538 (AM6538) is a potent, selective cannabinoid receptor CB1 antagonist with Ki of 5.1 nM.. |
| PC-45531 |
JD-5037
CB1 antagonist
|
JD-5037 is a potent, selective and peripherally restricted cannabinoid-1 (CB1) receptor blocker with IC50 of 2 nM, does not inhibit CB2 receptor (IC50>1000 nM). |
| PC-42171 |
Bay 59-3074
CB1/CB2 agonist
|
Bay 59-3074 is a potent, selective cannabinoid CB1/CB2 receptor partial agonist with Ki of 48.3, and 45.5 nM for human CB1 and human CB2 receptors, respectively. |
| PC-42063 |
Taranabant
CB1 inverse agonist
|
Taranabant (MK-0364) is a potent, selective and orally active cannabinoid-1 receptor (CB1R) inverse agonist with IC50 of 2.8 nM, Ki of 0.13 nM. |
| PC-42723 |
Otenabant
CB1 antagonist
|
Otenabant (CP-945598) is a potent, and selective CB1 receptor antagonist with Ki of 0.7 nM/0.12 nM in binding and functional assays respectively. |
| PC-23401 |
CB2 agonist 4Q3C
CB2 agonist
|
4Q3C is a selective CB2 receptor agonist, has selectivity index 10,000 more over CB1. |
