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Chemical Structure : Org 27569
CAS No.: 868273-06-7
Catalog No.: PC-43465Not For Human Use, Lab Use Only.
Org 27569 is a potent, selective, allosteric modulator of cannabinoid CB1 receptor, significantly increases the binding of the CB1 receptor agonist [3H]CP 55,940 with pKb of 5.67.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 50 mg | Get quote |
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Org 27569 is a potent, selective, allosteric modulator of cannabinoid CB1 receptor, significantly increases the binding of the CB1 receptor agonist [3H]CP 55,940 with pKb of 5.67.
Org 27569 reduces food consumption in rats, produces CB1-independent hypophagic effects and does not affect the discriminative stimulus effects of anandamide (AEA).
| M.Wt | 409.95 | |
| Formula | C24H28ClN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 52.2 mg/mL |
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| Chemical Name/SMILES |
1H-Indole-2-carboxamide, 5-chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]- |
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1. Price MR, et al. Mol Pharmacol. 2005 Nov;68(5):1484-95.
2. Erdozain AM, et al. Biochem Pharmacol. 2012 Jan 15;83(2):260-8.
3. Fay JF, et al. J Biol Chem. 2012 Sep 28;287(40):33873-82.
4. Gamage TF, et al. Behav Pharmacol. 2014 Apr;25(2):182-5.
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