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PrNMI

Chemical Structure : PrNMI

CAS No.: 1541244-33-0

PrNMI

Catalog No.: PC-35125Not For Human Use, Lab Use Only.

PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist with Ki of 1.18 nM and EC50 of 182 nM (hCB1R).

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Biological Activity

PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist with Ki of 1.18 nM and EC50 of 182 nM (hCB1R).
PrNMI significantly alleviates spontaneous pain behaviors in animals.

Physicochemical Properties

M.Wt 409.573
Formula C29H31NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-{2-[-(1E)-1[(4-propylnaphthalen-1-yl)methylidene]-1H-inden-3-yl]ethyl}morpholine

References

1. Zhang H, et al. Pain. 2018 May 16. doi: 10.1097/j.pain.0000000000001278.
2. Herbert H Seltzman, et al. J Med Chem. 2016 Aug 25;59(16):7525-43.

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