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Chemical Structure : WIN 55,212-2 mesylate
CAS No.: 131543-23-2
Catalog No.: PC-43469Not For Human Use, Lab Use Only.
WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $128 | In stock | |
| 50 mg | $198 | In stock | |
| 100 mg | $458 | In stock | |
| 500 mg | Get quote |
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WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively.
WIN 55,212-2 increases extracellular glutamate levels, displaying a bell-shaped concentration-response curve at 0.01-100 nM.
WIN 55,212-2 increases dialysate glutamate levels the prefrontal cortex from of the awake rats, also demonstrates anticonvulsant effect in vivo pre-treated with 20 mg/kg of pioglitazone.
| M.Wt | 522.61 | |
| Formula | C28H30N2O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Methanone, [(3R)-2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenyl-, methanesulfonate (1:1) |
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1. Felder CC, et al. Mol Pharmacol. 1995 Sep;48(3):443-50.
2. Griffin G, et al. J Pharmacol Exp Ther. 1998 May;285(2):553-60.
3. D'Ambra TE, et al. J Med Chem. 1992 Jan;35(1):124-35.
4. Martellotta MC, et al. Neuroscience. 1998 Jul;85(2):327-30.
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