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Chemical Structure : SMM-295
Catalog No.: PC-60810Not For Human Use, Lab Use Only.
SMM-295 is a potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM, >30-fold selectivity over CB1.
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SMM-295 is a potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM, >30-fold selectivity over CB1.
SMM-295 reduces cAMP production with a 66-fold selectivity for the CB2 versus the cannabinoid receptor 1 (CB1) in HEK-293 cells.
SMM-295 reduces tubular damage and plasma markers of renal dysfunction (i.e., creatinine and NGAL) in acute kidney injury mice.
| M.Wt | 324.438 | |
| Formula | C20H20O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Pressly JD, et al. J Pharmacol Exp Ther. 2017 Nov 29. pii: jpet.117.245522.
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