| Cat. No. |
Product Name |
Information |
| PC-20078 |
URB447
CB1R antagonist
|
URB447 (URB-447) is a peripherally restricted CB(1) antagonist/CB(2) agonist with IC50 of 313 nM (rat CB1) and 41 nM (human CB2). |
| PC-20077 |
AM6545
CB1R antagonist
|
AM6545 (AM-6545) is a potent, selective, oral bioavailable and non-brain-penetrant neutral CB1R antagonist with Ki of 3.3 nM, >100-fold selectivity over CB2R. |
| PC-20051 |
MRL-650
CB1R inhibitor
|
MRL-650 (MRL650) is a potent, selective inverse agonist of CB1 cannabinoid receptor with IC50 of <10 nM. |
| PC-49218 |
S-777469
CB2 agonist
|
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1. |
| PC-49031 |
PSB-CB-148
GPR18 antagonist
|
PSB-CB-148 is a potent, selective antagonist of GPR18. |
| PC-49030 |
PSB-KD107
GPR18 agonist
|
PSB-KD107 is a potent, selective GPR18 receptor agonist with EC50 of 0.562 uM and 1.78 uM for human and mouse GPR18, respectively. |
| PC-49029 |
PSB-CB-27
GPR18 antagonist
|
PSB-CB-27 is a potent, selective antagonist of GPR18 with IC50 of 650 nM, shows no inhibition on GPR55 and low affinity for CB1/CB2 receptors. |
| PC-47097 |
LY2828360
CB2 agonist
|
LY2828360 is a potent CB2 receptor agonist with similar affinity for human and rat CB2 receptors with Ki of 40.3 nM and 36.7 nM, respectively, shows EC50 of 20.1 nM in [35S]-GTPγS assays. |
| PC-38638 |
JM-00266
CB1 inverse agonist
|
JM-00266 is a novel non-brain penetrant cannabinoid receptor 1 (CB1R) inverse agonist with cAMP EC50 of 248.6 nM in HEK293T/17 cells transfected with murine CB1R. |
| PC-73457 |
Zevaquenabant
CB1R/iNOS inhibitor
|
Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual CB1 receptor/iNOS inhibitor. |
| PC-73454 |
Vicasinabin
CB2 agonist
|
Vicasinabin (RG7774, RG-7774) is a potent, selective agonist of cannabinoid receptor 2 (CB2) with cAMP EC50 of 1 nM (hCB2), >800-fold selectivity over CB1 receptor. |
| PC-73251 |
ZCZ011
CB1 receptor PAM
|
ZCZ011 is a positive allosteric modulator of CB1 receptor, increases specific binding of CB1 receptor orthosteric agonist [3H]CP55,940 to mouse brain membranes with pEC50 of 6.9. |
