| Cat. No. |
Product Name |
Information |
| PC-35592 |
AM9405
CB1/5-HT3 agonist
|
AM9405 (AM-9405, GAT-379) is novel potent, peripherally active cannabinoid type 1 (CB1) and 5-HT3 receptor agonist, inhibits the EFS-induced twitch contraction of the ileum and the colon with IC50 of 0.076 and 45.71 nM, respectively. |
| PC-35536 |
VCE-004.3
PPARγ/CB2 agonist
|
VCE-004.3 (VCE004.3) is a novel semi-synthetic cannabidiol derivative behaving as a dual PPARγ/CB2 agonist and CB1 receptor modulator, binds and activates PPARγ (IC50=3.5 uM) and CB2 receptors (pKi=6.69) and antagonizes CB1 receptor (pKi=5.61). |
| PC-35488 |
GAT100
CB1R modulator
|
GAT-100 (GAT100) is a potent, selective CB1R negative allosteric modulator (NAM) with cAMP EC50 and β-arr EC50 of 174 nM and 2.1 nM, does not exhibit inverse agonism. |
| PC-35485 |
GAT211
CB1R modulator
|
GAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM. |
| PC-35125 |
PrNMI
CB1 agonist
|
PrNMI is a peripherally restricted cannabinoid 1 receptor (CB1R) agonist with Ki of 1.18 nM and EC50 of 182 nM (hCB1R). |
| PC-43469 |
WIN 55,212-2 mesylate
Cannabinoid receptor agonist
|
WIN 55,212-2 mesylate (WIN 55212-2) is a potent cannabinoid receptor agonist with Ki of 62.3 and 3.3 nM for human recombinant CB1 and CB2 receptors, respectively. |
| PC-43465 |
Org 27569
CB1R modulator
|
Org 27569 is a potent, selective, allosteric modulator of cannabinoid CB1 receptor, significantly increases the binding of the CB1 receptor agonist [3H]CP 55,940 with pKb of 5.67. |
| PC-43210 |
DBPR211
CB1 antagonist
|
DBPR211 (BPRCB1184, CB1-IN-4) is a potent, selective, peripherally restricted cannabinoid-1 (CB1) receptor antagonist with Ki of 0.3 nM, EC50 of 3.0 nM. |
| PC-43187 |
A-836339
CB2 agonist
|
A-836339 (A836339) is a potent and selective cannabinoid CB2 receptor agonist with Ki of 0.64 and 0.76 nM for human and rat CB2 receptors, displays 425- and 189-fold selectivity over CB1 receptor, respectively. |
| PC-63019 |
LDK1229
CB1 inverse agonist
|
LDK1229 is a novel potent, selective cannabinoid CB1 receptor inverse agonist with Ki of 220 nM. |
| PC-62915 |
MK-9470
CB1 inverse agonist
|
MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging.. |
| PC-60810 |
SMM-295
CB2 agonist
|
SMM-295 is a potent, selective cannabinoid receptor 2 (CB2) agonist with Ki of 12 nM, >30-fold selectivity over CB1. |
