Catalog No.: PC-49218Not For Human Use, Lab Use Only.
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1.
S-777469 (S777469) is a potent, selective, orally available cannabinoid receptor 2 (CB2) receptor agonist with Ki value of 32 nM (hCB2), >100-fold selectivity over CB1.
S-777469 significantly suppressed scratching behavior induced by histamine or substance P in mice or by serotonin in rats.
S-777469 significantly suppressed DNFB-induced ear swelling in a dose-dependent manner.
S-777469 significantly alleviated mite antigen-induced atopic dermatitis-like skin lesions in NC/Nga mice.
