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MK-9470

Chemical Structure : MK-9470

CAS No.: 945850-36-2

MK-9470 (MK9470)

Catalog No.: PC-62915Not For Human Use, Lab Use Only.

MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MK-9470 is a potent, selective cannabinoid CB1 receptor (CB1R) inverse agonist with IC50 of 0.7 nM, 18F MK-9470 has been developed for use in human brain imaging.

    Physicochemical Properties

    M.Wt 471.59
    Formula C29H33N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[(2S,3S)-3-(3-cyanophenyl)-4-(4-ethoxyphenyl)butan-2-yl]-2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide

    References

    1. Burns HD, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5.

    2. Van Laere K, et al. J Nucl Med. 2008 Mar;49(3):439-45.

    3. Gérard N, et al. J Mol Neurosci. 2010 Oct;42(2):162-7.

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