| Cat. No. |
Product Name |
Information |
| PC-22541 |
PSB-KK1445
GPR18 agonist
|
PSB-KK1445 is a potent and selective GPR18 agonist with EC50 of 45.4 nM and 124 nM for human and mouse GPR18, respectively, shows high selectivity versus related GPCRs CB1 and CB2, cannabinoid-like receptor, GPR55. |
| PC-22540 |
YK-4-279
EWS-FLI1 inhibitor
|
YK-4-279 is a specific small molecule inhibitor of EWS-FLI1 interaction with RNA helicase A with SPR KD of 9.48 uM for EWS-FLI1, reduces EWS-FLI1 functional activity, also reduces EWS-FLI1 modulated transcription. |
| PC-22489 |
UR778Br
IQGAP1 inhibitor
|
UR778Br is a potent small molecule inhibitor of scaffolding protein IQGAP1, taregting the IQGAP1-GRD domain, selectively inhibits growth of human acute myeloid leukemia. |
| PC-22481 |
Forchlorfenuron
Septin inhibitor
|
Forchlorfenuron (CPPU, 4PU30) is a substituted phenylurea compound and synthetic plant cytokinin for inducing somatic embryogenesis in peanut (Arachis hypogaea L.), inhibits septin and protrusion formation. |
| PC-22470 |
PW0729
GPR52 agonist
|
PW0729 is a potent, selective, G protein-biased agonist of orphan GPR52 with EC50 of 47 nM in cAMP assay, Emax=143%. |
| PC-22469 |
BI-43
Glutaminyl cyclase inhibitor
|
BI-43 is a potent, selective glutaminyl cyclase inhibitor with IC50 of 12 nM and 40 nM for both sQC and gQC, respectively. |
| PC-22463 |
HTRA1 inhibitor 17
HTRA1 inhibitor
|
HTRA1 inhibitor 17 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 13 nM. |
| PC-22462 |
HTRA1 inhibitor 10
HTRA1 inhibitor
|
HTRA1 inhibitor 10 is a highly potent and selective inhibitor of high temperature requirement A serine peptidase 1 (HTRA1) serine protease with IC50 of 10 nM. |
| PC-22460 |
DC-5163
GAPDH inhibitor
|
DC-5163 is a smal molecule glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor with IC50 of 176.3 nM, inhibits glucose uptake, reduces lactic acid production, selectively inhibits cancer cell proliferation. |
| PC-22448 |
CMFT
MIF inhibitor
|
CMFT is a a small molecule inhibitor of the functional interaction between the transcription factor ICBP90 (a.k.a. UHRF1) and the MIF-794 CATT5-8 promoter microsatellite, inhibits MIF mRNA expression in a -794 CATT5-8 length-dependent manner with an IC50 of 470 nM. |
| PC-22443 |
P4B
Cellulose biosynthesis inhibitor
|
P4B is a small molecule cellulose biosynthesis inhibitor of Arabidopsis (Arabidopsis thaliana) seedling growth. |
| PC-22442 |
UCM-13369
NPM1 inhibitor
|
UCM-13369 is a small molecule inhibitor of nucleophosmin 1 (NPM1), inhibits NPM1 expression, downregulates the pathway associated with mutant NPM1 C+, inhibits tumorsphere growth of CSCs. |
