| Cat. No. |
Product Name |
Information |
| PC-62184 |
trans Ned-19
|
trans Ned-19 is a cell-permeant chemical probe for the Ca(2+)-releasing second messenger NAADP, blocks NAADP signaling (IC50=6 nM, inhibition of Ca2+ release). |
| PC-62183 |
cis Ned-19
|
cis Ned-19 is the stereoisomer of trans Ned-19, a chemical probe for the Ca(2+)-releasing second messenger NAADP. |
| PC-62153 |
GGTI 2418 sodium
|
GGTI 2418 sodium (PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
| PC-62124 |
ML387
|
ML387 (CID3474778) is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 19 nM. |
| PC-62123 |
ML388
|
ML388 is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 34 nM. |
| PC-62119 |
ML377
|
ML377 (MLS 0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.. |
| PC-62114 |
Isoquercetin
|
Isoquercetin is a flavonoid and 3-O-glucoside of quercetin that displays selective cytotoxicity to cancer cells, primarily by inducing apoptosis and cell cycle arrest.. |
| PC-62075 |
Gerfelin
|
Gerfelin is an osteoclastogenesis inhibitor (IC50=61 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.15 uM. |
| PC-62074 |
Methyl Gerfelin
|
Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM. |
| PC-62073 |
Surfen hydrate
|
Surfen hydrate is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62072 |
Surfen
|
Surfen is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62062 |
CMA-008
|
CMA-008 is a cell-permeable, small molecule modulator of NAADP-mediated Ca2+ release, competes with NAADP binding, inhibit Ca2+ release via the NAADP receptor (IC50=15 uM-1 mM). |
