| Cat. No. |
Product Name |
Information |
| PC-27431 |
(S)-Retro-2.1
Retrograde transport inhibitor
|
Retro-2.1a ((S)-Retro-2.1) is a potent molecule to counteract the cytotoxic potential of ricin and Shiga toxin with EC50 of 23 nM and 54 nM, respectively, blocking retrograde transport and intracellular retrograde trafficking. |
| PC-27430 |
Retro-2.1
Retrograde transport inhibitor
|
Retro-2.1 is a small molecule inhibitor of retrograde transport, protects human cells against ricin and Stx by blocking retrograde toxin transport at the early endosomes-TGN interface, efficiently inhibits SARS-CoV-2 replication, inhibits JC polyomavirus (JCPyV) with EC50 of 3.9 uM. |
| PC-27423 |
Enterobactin
Iron chelator
|
Enterobactin is an iron transport compound and iron chelator from Salmonella typhimurium, not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages during the process of Salmonella typhimurium infecting macrophages, is also involved in the oxidative stress response of Escherichia coli. |
| PC-27422 |
3,4,3-LI(1,2-HOPO)
Chelating agent
|
3,4,3-LI(1,2-HOPO) (Enfipaxetan) is a metal chelating agent, exhibits extremely high affinity for lanthanide metal ions, sensitizes the emission of Sm(III), Eu(III), and Tb(III) in the Visible range and the emission of Pr(III), Nd(III), Sm(III), and Yb(III). |
| PC-27405 |
APOL1-IN-1
APOL1 inhibitor
|
APOL1-IN-1 (Compound 87) is a small molecule inhibitor of apolipoprotein L1 (APOL1). |
| PC-27404 |
Alcedaplin
APOL1 inhibitor
|
Alcedaplin is a small molecule inhibitor of apolipoprotein L1 (APOL1) function. |
| PC-27395 |
BCT2029
BLVRB inhibitor
|
BCT2029 is a potent Biliverdin IXb reductase (BLVRB, biliverdin reductase IXβ) inhibitor, inhibits BLVRB reductive activity using both FMN (flavin mononucleotide, IC50=194 nM) and DCPIP (2,6-dichlorophenolindophenol; IC50=28 nM) as substrates. |
| PC-27394 |
BCT2102
BLVRB ligand
|
BCT2102 is a cell-permeable acceptor ligand of Biliverdin IXb reductase (BLVRB), demonstrates specific energy transfer and inform equilibrium binding affinities, target engagement, and residence time analyses in vitro and cellular nanoBRET assays. |
| PC-27393 |
BCT2101
BLVRB ligand
|
BCT2101 is a cell-permeable acceptor ligand of Biliverdin IXb reductase (BLVRB), demonstrates specific energy transfer and inform equilibrium binding affinities, target engagement, and residence time analyses in vitro and cellular nanoBRET assays. |
| PC-27391 |
[18F]FB-HTL
PET ligand
|
[18F]FB-HTL is a BBB-penetrable fluorine-18-labelled small-molecule HaloTag ligand and PET reporter ligand for quantitative imaging of gene expression in the brain. |
| PC-27390 |
Spermidine
CAS 124-20-9
|
Spermidine is a polyamine essential for various biological processes, has long been recognized as a signaling molecule, promotes cell growth, regeneration, and autophagy, targets GGA-rich small RNAs for virulence regulation. |
| PC-27388 |
ALOX15-IN-1
ALOX15 inhibitor
|
ALOX15-IN-1 (Compound 8b) is a potent, substrate-selective and allosteric inhibitor of mammalian Arachidonic acid 15-lipoxygenase (ALOX15) orthologs, inhibits linoleate oxygenase activity of rabbit and human ALOX15 with IC50 of 0.04 uM, without affecting arachidonic acid oxygenation. |
