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Diacerein

Chemical Structure : Diacerein

CAS No.: 13739-02-1

Diacerein (Diacerhein)

Catalog No.: PC-24030Not For Human Use, Lab Use Only.

Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect.

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100 mg $78 In stock
250 mg $128 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect.

Physicochemical Properties

M.Wt 368.30
Formula C19H12O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,5-Diacetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

References

1. Singh A, et al. Biochemistry. 2025 Jan 30. doi: 10.1021/acs.biochem.4c00535.

2. Birgit Lohberger, et al. BMC Cancer. 2015 Nov 10:15:891.

3. Shi S, et al. Front Pharmacol. 2020;11:560361.

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