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Cat. No. Product Name Information
PC-38194

AG-636

DHODH inhibitor

AG-636 (AG636) is a novel potent, selective, reversible and oral dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 17 nM.
PC-38179

VY-3-135

ACSS2 inhibitor

VY-3-135 is a potent, specific acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 44 nM, does not inhibits AcCoA synthetase family member ACSS1 and ACSS3.
PC-38168

BO-264

TACC3 inhibitor

BO-264 (BO264) is a highly potent inhibitor of transforming acidic coiled-coil (TACC) family member TACC3 (IC50=188 nM).
PC-38167

CHD1L inhibitor 6

CHD1L inhibitor

CHD1L inhibitor 6 is the first-in-class small molecule inhibitor of oncogenic CHD1L with IC50 of 5.5 uM in cat-CHD1L ATPase assay.
PC-38165

SBI-183

QSOX1 inhibitor

SBI-183 is a small molecule that binds to and inhibits the enzymatic activity of Quiescin sulfhydryl oxidase 1 (QSOX1, Kd=20 uM).
PC-38164

DSRM-3716

SARM1 inhibitor

DSRM-3716 (DSRM3716, 5-iodoisoquinoline) is a potent and selective inhibitor of NADase SARM1 with IC50 of 75 nM, displays selectivity against various NAD metabolizing and pathway enzymes (e.g., NAMPT and NMNAT).
PC-38163

ITYR-DBRMD

DIO3 inhibitor

ITYR-DBRMD is a first-in-class inhibitor of enzyme iodothyronine deiodinase type 3 (DIO3) with antitumor effects both in vitro and in vivo.
PC-38162

PBENZ-DBRMD

DIO3 inhibitor

PBENZ-DBRMD is a first-in-class inhibitor of enzyme iodothyronine deiodinase type 3 (DIO3) with antitumor effects both in vitro and in vivo.
PC-38159

CADD522

RUNX2 inhibitor

CADD522 (CADD-522) is a small molecule that inhibits RUNX2-DNA binding (IC50=10 nM) and decreases RUNX2 transcriptional activity.
PC-38158

SCL-LMO2 inhibitor 3K7

SCL-LMO2 inhibitor

SCL-LMO2 inhibitor 3K7 is a small molecule, specific inhibitor of the SCL-LMO2 PPI, binds directly to LMO2 with Kd of 1.2 uM.
PC-38147

eCIRP/TREM-1 inhibitor M3

eCIRP/TREM-1 inhibitor

eCIRP/TREM-1 inhibitor M3 (RGFFRGG) is a small CIRP-derived peptide that inhibits the eCIRP/TREM-1 interaction.
PC-38144

InhiTinib

IFN-gamma inhibitor

InhiTinib is a small molecule that inhibit interferon (IFN)-gamma production (IC50=52.44 nM) and proliferation of primary CD3+ T cells without inducing cell death.

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