| Cat. No. |
Product Name |
Information |
| PC-26910 |
CVM-05-002
PI5P4K inhibitor
|
CVM-05-002 is a potent and selective inhibitor of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) with IC50 of 0.27 uM and 1.69 uM for PI5P4Kα and PI5P4Kβ。 |
| PC-26909 |
066ATZ
PIP4K2A/2B inhibitor
|
066ATZ is a potent, selective dual PIP4K2A and PIP4K2B inhibitor with Ki of 100 nM and 800 nM. |
| PC-26907 |
Fexlamose
Mucolytic
|
Fexlamose (AER-01, MUC-031) is a potent and fast-acting mucolytic compound, cleaves disulfides to cause mucolysis, shows potential for muco-obstructive lung diseases like COPD (Chronic Obstructive Pulmonary Disease) and asthma. |
| PC-26904 |
ADGRL1 inhibitor compound 2
ADGRL1 inhibitor
|
ADGRL1 inhibitor compound 2 is a potential small molecule inhibitor of adhesion G protein-coupled receptor L1 (ADGRL1/Latrophilin-1), activates the GSK3β-STAT1 axis in CT26 cells in vitro, consistent with the knockdown of Adgrl1. |
| PC-26902 |
CPN-351 TFA
NMUR1 antagonist
|
CPN-351 TFA is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26901 |
CPN-351
NMUR1 antagonist
|
CPN-351 is a potent, selective pentapeptide antagonist of Neuromedin U Receptor 1 (NMUR1) with pA2 and KB values of 7.35 and 45 nM, respectively, selective over NMUR2 with 6.38 and 421 nM, respectively. |
| PC-26890 |
Sinbaglustat
GCS/GBA2 inhibitor
|
Sinbaglustat (OGT2378) is an orally available, blood-brain barrier permeable dual inhibitor of glucosylceramide synthase (GCS) and non-lysosomal glucosyl ceramidase (GBA2), Sinbaglustat is 50‐fold more potent in inhibiting GBA2 than GCS. |
| PC-26885 |
Tetrahydrocurcumin
36062-04-1
|
Tetrahydrocurcumin (THC, LG0367) is a antioxidative metabolite of curcumin, inhibits radiation-induced lipid peroxidation in rat liver microsomes, also suppresses melanin content and tyrosinase activity. |
| PC-26882 |
SIH-002
ZMIZ1 inhibitor
|
SIH-002 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.16 uM. |
| PC-26881 |
SIH-001
ZMIZ1 inhibitor
|
SIH-001 is a specific small-molecule inhibitor of ZMIZ1 (Zinc finger MIZ domain-containing protein 1) with SPR KD of 0.498 uM. |
| PC-26874 |
A-3190
CD38 inhibitor
|
A-3190 is a potent, selective, brain-penetrant CD38 inhibitor with IC50 of 7.2 nM and 1.2 nM for human and mouse CD38 respectively. |
| PC-26873 |
A-8531
CD38 inhibitor
|
A-8531 is a potent, selective, peripheral CD38 inhibitor with IC50 of 0.4 nM and 3.6 nM for human and mouse CD38 respectively. |
