| Cat. No. |
Product Name |
Information |
| PC-21628 |
RBS-10
NQO1 inhibitor
|
RBS-10 is a small molecule that shows preferential cytotoxicity against cells pan-resistant to degraders, acts as a prodrug bioactivated by the oxidoreductase enzyme NQO1. |
| PC-21627 |
JA310
MST3 (STK24) inhibitor
|
JA310 is a potent, highly selective inhibitor of the mammalian sterile 20-like serine/threonine (MST) family member MST3 (STK24) with ITC KD value of 115 nM. |
| PC-21625 |
BK697
FIRΔexon2 inhibitor
|
BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions. |
| PC-21595 |
7-Fluorotryptamine
GPRC5A agonist
|
7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
| PC-21594 |
7-Fluorotryptamine hydrochloride
GPRC5A agonist
|
7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
| PC-21588 |
3-mercaptopicolinic acid hydrochloride
PEPCK inhibitor
|
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK, PCK) inhibitor with Ki of 2-9 uM, an inhibitor of gluconeogenesis. |
| PC-21580 |
CHD1Li 11
CHD1L inhibitor
|
CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
| PC-21551 |
AQIM-I
ILF3/NF110 inhibitor
|
AQIM-I is a highly potent small molecule survivin inhibitor by targeting ILF3/NF110, binds to ILF3/NF110 with KD value of 163 nM in SPR assays, has broad-spectrum antitumor activity. |
| PC-21548 |
AEP inhibitor 18
APE inhibitor
|
AEP inhibitor 18 is a potent, selective, orally bioavailable, and brain penetrant inhibitor of asparagine endopeptidase (AEP) with IC50 of 7.8 nM. |
| PC-21541 |
PT-91
GPR27 agonist
|
PT91 is a small-molecule GPR27 (SREB1) agonist with pEC50 of 6.15 (human GPR27) in β-arrestin 2 recruitment-based firefly luciferase complementation assay, Emax=100%. |
| PC-21516 |
HJ445A
Myoferlin inhibitor
|
HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
| PC-21492 |
AP736
|
AP736 is a damantyl benzylbenzamide derivative with anti-melanogenic effects in melanocytes in vitro, acts via the downregulation of tyrosinase, TRP-1 and MITF expression. |
