| Cat. No. |
Product Name |
Information |
| PC-21594 |
7-Fluorotryptamine hydrochloride
GPRC5A agonist
|
7-fluorotryptamine (7FTA) is a potent synthetic agonist of GPRC5A with EC50 of 7.2 uM for inducing GPRC5A-mediated β-arrestin recruitment. |
| PC-21588 |
3-mercaptopicolinic acid hydrochloride
PEPCK inhibitor
|
SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK, PCK) inhibitor with Ki of 2-9 uM, an inhibitor of gluconeogenesis. |
| PC-21580 |
CHD1Li 11
CHD1L inhibitor
|
CHD1Li 11 (CHD1L inhibitor 11) is a small molecule inhibitor of chromodomain helicase DNA-binding protein 1 like (CHD1L) with IC50 of 4.57 uM. |
| PC-21575 |
BiTud
TDRD3 inhibitor
|
BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibits the stress granule growth in cells. |
| PC-21551 |
AQIM-I
ILF3/NF110 inhibitor
|
AQIM-I is a highly potent small molecule survivin inhibitor by targeting ILF3/NF110, binds to ILF3/NF110 with KD value of 163 nM in SPR assays, has broad-spectrum antitumor activity. |
| PC-21548 |
AEP inhibitor 18
APE inhibitor
|
AEP inhibitor 18 is a potent, selective, orally bioavailable, and brain penetrant inhibitor of asparagine endopeptidase (AEP) with IC50 of 7.8 nM. |
| PC-21541 |
PT-91
GPR27 agonist
|
PT91 is a small-molecule GPR27 (SREB1) agonist with pEC50 of 6.15 (human GPR27) in β-arrestin 2 recruitment-based firefly luciferase complementation assay, Emax=100%. |
| PC-21516 |
HJ445A
Myoferlin inhibitor
|
HJ445A is a highly potent, selective myoferlin (MYOF) inhibitor, binds to MYOF-C2D domain with KD value of 0.17 uM. |
| PC-21492 |
AP736
|
AP736 is a damantyl benzylbenzamide derivative with anti-melanogenic effects in melanocytes in vitro, acts via the downregulation of tyrosinase, TRP-1 and MITF expression. |
| PC-21475 |
AGI-43192
MAT2A inhibitor
|
AGI-43192 is a potent and selective methionine adenosyltransferase 2A (MAT2A) inhibitor with cellular IC50 of 14 nM. |
| PC-21474 |
AGI-41998
MAT2A inhibitor
|
AGI-41998 is a potent selective and brain-penetrant methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 22 nM. |
| PC-21472 |
RTI-118
NPSR antagonist
|
RTI-118 is a potent, selective neuropeptide S receptor (NPSR, GPR154) antagonist. |
