LY3475070 | CD73 inhibitor | Probechem Biochemicals

Chemical Structure : LY3475070

CAS No.: 2375815-63-5

LY3475070 (LY-3475070)

Catalog No.: PC-38017Not For Human Use, Lab Use Only.

LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.

Packing	Price	Stock
5 mg	$198	In stock
25 mg	$398	In stock
50 mg	$598	In stock
100 mg	$998	In stock
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Biological Activity

LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.

Physicochemical Properties

M.Wt	286.335
Formula	C15H18N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione

References

1. Elizabeth A. Thompson, et al. Annu Rev Med. 2022 Jan 27.

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LY3475070 (LY-3475070)

Biological Activity

Physicochemical Properties

References

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