Chemical Structure : LY3475070
CAS No.: 2375815-63-5
Catalog No.: PC-38017Not For Human Use, Lab Use Only.
LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.
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LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.
M.Wt | 286.335 | |
Formula | C15H18N4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione |
1. Elizabeth A. Thompson, et al. Annu Rev Med. 2022 Jan 27.
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