| Cat. No. |
Product Name |
Information |
| PC-70314 |
SI-2 hydrochloride
SRC-3 inhibitor
|
A potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. |
| PC-70313 |
SI-2
SRC-3 inhibitor
|
SI-2 (EPH-116) is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. |
| PC-70287 |
PDZ1i
MDA-9/Syntenin inhibitor
|
PDZ1i (113B7) is a specific inhibitor of MDA-9/Syntenin activity that inhibits MDA-9/Syntenin binding to EGFRvIII. |
| PC-70286 |
FD-44
|
FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model. |
| PC-70281 |
CBR-096-4
|
CBR-096-4 is a derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues. |
| PC-61205 |
XEN 602
DMT1 inhibitor
|
XEN 602 (XEN602) is a potent, specific divalent metal transporter 1 (DMT1) inhibitor that inhibits Mn incorporation in HEK293 cells with IC50 of 0.3 nM. |
| PC-61196 |
FPH1
iPS differentiation inducer
|
FPH1 (BRD6125) is a small molecule that induces functional proliferation of hepatocytes in vitro, increases expansion of primary human hepatocytes and induces maturation of hepatocyte-like cells (iHeps). |
| PC-61190 |
CCT 365623 hydrochloride
Lysyl oxidase inhibitor
|
CCT 365623 (CCT365623) hydrochloride is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
| PC-61189 |
CCT365623
LOX inhibitor
|
CCT365623 (CCT-365623) is a potent, orally active small molecule inhibitor of lysyl oxidase (LOX) with IC50 of 0.89 uM. |
| PC-61188 |
Barbadin
|
Barbadin is a small molecule that selectively inhibits the β-arrestin/β2-adaptin interaction (IC50=19.1/15.6 uM for β-arrestin1/2) without effect on the formation of receptor/β-arrestin complexes. |
| PC-61182 |
KPT-6566
Pin1 inhibitor
|
KPT-6566 (KPT6566) is a potent, specific and covalent inhibitor of the prolyl isomerase PIN1 with Ki of 625.2 nM, IC50 of 0.64 uM. |
| PC-61128 |
PAT-1251
LOXL2 inhibitor
|
Lenumlostat (GB2064, PAT1251) is a potent, selective and orally bioavailable lysyl oxidase-like 2 (LOXL2) inhibitor with IC50 of 0.71 uM in human whole blood assays, with high selectivity over LOX (400-fold) and other amine oxidases. |
