| Cat. No. |
Product Name |
Information |
| PC-60880 |
ZINC 39395747
CYB5R3 inhibitor
|
ZINC 39395747 is a novel potent derivative of propylthiouracil that functions as a cell-active inhibitor of cytochrome b5 reductase 3 (CYB5R3) with IC50 of 9.14 uM. |
| PC-50007 |
BRD10330
IL-10 inducer
|
BRD10330 (BRD-10330) is a small molecule that upregulates IL-10 production in BMDCs. |
| PC-60849 |
ADDA 5
Cytochrome c oxidase inhibitor
|
ADDA 5 is a specific, non-competitive, small molecule cytochrome c oxidase (CcO or complex IV) inhibitor with IC50 of 18.93 uM (CcO from human glioma). |
| PC-60717 |
TK05
LTC4S inhibitor
|
TK05 is a potent and selective inhibitors of leukotriene C4 synthase (LTC4S) with IC50 of 95 nM, Ki of 6 nM. |
| PC-60714 |
PRD125
ACAT2 inhibitor
|
PRD125 is a potent and selective inhibitor of sterol O-acyltransferase 2 (SOAT2, ACAT2) with IC50 of 11.8 nM, >6,000-fold selectivity over ACAT1. |
| PC-60694 |
LX2931
S1P lyase inhibitor
|
LX-2931 (LX2931) is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor. |
| PC-60693 |
S1P Lyase inhibitor 31
S1PL inhibitor
|
S1P Lyase inhibitor 31 is a potent, selective and orally bioavailable S1P lyase (S1PL) inhibitor with enzyme IC50 of 44 nM, cell IC50 of 110 nM. |
| PC-60680 |
ES936
NQO1 inhibitor
|
ES936 is a potent, specific mechanism-based human NAD(P)H: quinone oxidoreductase 1 (NQO1) inhibitor that demonstrates efficient inactivation of NQO1 at 100 nM in in cellular systems. |
| PC-60677 |
AR03
APE1 inhibitor
|
AR03 (BMH-23, AR03, Ape1 repair inhibitor 03) is a novel small molecule inhibitor of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) endonuclease activity with IC50 of 5 uM. |
| PC-60661 |
PD 404182
DDAH1 inhibitor
|
PD 404182 (PD404182, PD-404182) is a heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels. |
| PC-60650 |
Ru360
MCU inhibitor
|
Ru360 is a cell-permeable mitochondrial calcium uptake (MCU) inhibitor that binds to mitochondria with high affinity (Kd=340 pM) and blocks Ca2+ uptake into mitochondria in vitro with IC50 of 184 pM. |
| PC-60649 |
AG311
Necrosis inducer
|
AG311 is a first-in-class antitumor and antimetastatic agent that induces necrosis in breast cancer tumors, inhibits inhibit mitochondria complex I activity and reduces HIF-1α stabilization. |
