| Cat. No. |
Product Name |
Information |
| PC-62386 |
P11
PAFAH inhibitor
|
PAFAH1b2/1b3-IN-P11 (P11) is a potent, selective platelet-activating factor acetylhydrolases PAFAH1b2 and PAFAH1b3 inhibitor with IC50 of 40 nM and 900 nM respectively. |
| PC-62382 |
RH01687
|
RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death. |
| PC-62380 |
TD-1
Hemoglobin modulator
|
Hemoglobin modulator TD-1 (TD-1) is a novel allosteric effector of hemoglobin that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling. |
| PC-62379 |
BCI-137
AGO2 inhibitor
|
BCI-137 is a chemical compound able to compete with Argonaute 2 (Ago2) miRNAs binding, binds to Ago2 with Kd of 126 uM. |
| PC-62369 |
BRD56491
ROS inducer
|
BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62368 |
BRD9092
ROS inducer
|
BRD9092 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62367 |
BRD5459
ROS inducer
|
BRD5459 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death, ROS inducer.. |
| PC-62363 |
MN30
APOBEC3G inhibitor
|
MN30 (Methyl-3,4-dephostatin, APOBEC3G inhibitor MN30) is a first-in-class, selectve small molecule inhibitor of the single-strand DNA cytosine deaminase APOBEC3G with IC50 of 9.1 uM. |
| PC-62361 |
Aurintricarboxylic acid
|
NSC4056 (Aurintricarboxylic acid) is a potent, bioactive inhibitor of cystathionine γ-lyase (CSE) with IC5 of 0.6 uM, also is a selective inhibitor of the TWEAK-Fn14 signaling pathway. |
| PC-62356 |
BIO 8898
CD40L inhibitor
|
BIO 8898 is a synthetic, CD40-CD154 co-stimulatory interaction inhibitor that inhibits the TNF family cytokine CD40L binding to CD40-Ig with a potency of IC50=25 uM. |
| PC-62343 |
Deoxynyboquinone
NQO1 substrate
|
Deoxynyboquinone (NSC 165572, DNQ) is a potent inducer of cancer cell death that induces death of cancer cells in culture with IC50 of 16-210 nM, a substrate for NAD(P)H:quinone oxidoreductase (NQO1). |
| PC-62342 |
Isobutyl-deoxynyboquinone
NQO1 substrate
|
Isobutyl-deoxynyboquinone (IB-DNQ) is a selective substrate for NAD(P)H:quinone oxidoreductase (NQO1), produces ROS, and induces cytotoxicity in cancer cells in an NQO1-dependent manner. |
