| Cat. No. |
Product Name |
Information |
| PC-62075 |
Gerfelin
Glyoxalase I inhibitor
|
Gerfelin is an osteoclastogenesis inhibitor (IC50=61 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.15 uM. |
| PC-62074 |
Methyl Gerfelin
Glyoxalase I inhibitor
|
Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM. |
| PC-62073 |
Surfen hydrate
Heparan sulfate antagonist
|
Surfen hydrate is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62072 |
Surfen
Heparan sulfate antagonist
|
Surfen is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62062 |
CMA-008
NAADP inhibitor
|
CMA-008 is a cell-permeable, small molecule modulator of NAADP-mediated Ca2+ release, competes with NAADP binding, inhibits Ca2+ release via the NAADP receptor (IC50=15 uM-1 mM). |
| PC-62061 |
BZ194
NAADP inhibitor
|
BZ194 (BZ-194) is a small molecule inhibitor of NAADP action that inhibit NAADP-mediated Ca2+ signaling in T cells, neither interferes with Ca2+ mobilization by IP3 or cyclic ADP-ribose nor with capacitative Ca2+ entry. |
| PC-62059 |
FSC231
PICK1 inhibitor
|
FSC231 (FSC-231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
| PC-62048 |
MitoBloCK 6
Erv1 oxidase inhibitor
|
MitoBloCK 6 is a small molecule mitochondrial protein import blocker that inhibits Erv1 oxidase activity. |
| PC-62047 |
MitoBloCK 1
TIM22 inhibitor
|
MitoBloCK 1 is a small molecule inhibitor that blocks the import of substrates that use the TIM22 import pathway, but not TIM23 or the Mia40/Erv1 translocation pathways. |
| PC-62043 |
DM-PIT-1
PIP3 antagonist
|
DM-PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain, PIP3/PDK1 PH domain, and PIP3/GRP1 PH domain with IC50 of 27.1 uM, 80.5 uM, and 35.5 uM, respectively. |
| PC-62042 |
PIT-1
PIP3 antagonist
|
PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain binding with IC50 of 30 uM, Kd of 43.2 uM. |
| PC-62033 |
LCS-1.34
SOD1 inhibitor
|
LCS-1.34 is a small molecule that inhibits growth of human lung adenocarcinoma cells harboring mutations in EGFR or KRAS with IC50 of 0.1-1.1 uM. |
