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GAPDS

Chemical Structure : GAPDS

CAS No.: 917773-99-0

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GAPDS (GAPDH inhibitor GAPDS)

Catalog No.: PC-62489Not For Human Use, Lab Use Only.

GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH).
    GAPDS significantly reduces cellular ATP, shows greater toxicity against cancer cells compared to 6-OHDA, also selectively inhibits cell migration and invasion.
    GAPDS reduces GAPDH levels in the cytoplasm, and has potent anticancer activity in vivo.

    Physicochemical Properties

    M.Wt 573.654
    Formula C30H35N7O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-(2-(2-((4-((3,4-dihydroxyphenethyl)amino)-6-(phenylamino)-1,3,5-triazin-2-yl)amino)ethoxy)ethoxy)ethyl)benzamide

    References

    1. Jung DW, et al. Chem Biol. 2014 Nov 20;21(11):1533-45.

    2. Min J, et al. Nat Chem Biol. 2007 Jan;3(1):55-9.

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