Cat. No. |
Product Name |
Information |
PC-72380 |
SUCNR1 inhibitor 20
SUCNR1 (GPR91) antagonist
|
SUCNR1 inhibitor 20 is a potent, selective inhibitor (antagonist) of GPCR SUCNR1 (succinate receptor 1/GPR91) with IC50 of 88 nM. |
PC-72370 |
Ophiobolin A
Calmodulin inhibitor
|
Ophiobolin A (OphA) is a potent, covalent CaM inhibitor, with broad toxicity against plants, microbes, and cancer cells, OphA also is a K-Ras4B but not an H-Ras selective inhibitor. |
PC-72352 |
Calmirasone1
Calmodulin inhibitor
|
Calmirasone1 (Calmirasone 1) is a novel and potent covalent calmodulin (CaM) inhibitor with Kd of 0.87 uM. |
PC-72348 |
FT113
FASN inhibitor
|
FT113 (FT-113) is a potent inhibitor of fatty acid synthase (FASN) with IC50 of 213 nM (hFASN). |
PC-72347 |
JNJ-54302833
FASN inhibitor
|
JNJ-54302833 (JNJ 54302833) is a potent, selective fatty acid synthase (FASN) inhibitor with IC50 of 28 nM. |
PC-72338 |
AGI-25696
MAT2A inhibitor
|
AGI-25696 (AGI 25696) is a potent and selective inhibitor of methionine adenosyltransferase MAT2A, blocks the growth of MTAP-deleted tumors in vivo. |
PC-72335 |
Ironomycin
|
Ironomycin (Ironomycin AM5) is a lysosomal iron-targeting small molecule that reduces the mitochondrial iron load, resulting in the potent disruption of mitochondrial metabolism. |
PC-72301 |
SW2_110A
CBX8 inhibitor
|
SW2_110A (SW2-110A) is a selective, cell-permeable inhibitor of chromobox homolog protein CBX8, binds CBX8 N-terminal chromodomain (ChD) with Kd of 800 nM. |
PC-72298 |
CBX6 inhibitor 5
CBX6 inhibitor
|
CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively. |
PC-72285 |
TH-3021
AKR1C3 inhibitor
|
TH-3021 (SN336384) is a potent and specific inhibitor of AKR1C3 with IC50 of 110 nM in isolated enzyme assays and 18 nM in cellular assays, displays no inhibitory action against AKR1C1/1C2/1C4 (IC50>30 uM). |
PC-72270 |
SHR170008
CD73 inhibitor
|
SHR170008 is a highly potent, small molecule CD73 inhibitor with IC50 of 0.05 nM against human CD73 soluble enzyme. |
PC-72241 |
CBLC000
FACT inhibitor
|
CBLC000 (CBL0100) is a small molecule histone chaperone FACT inhibitor, activates p53 and inhibits NF-κB with EC50 of 0.06 and 0.03 uM in cell-based p53 and NF-κB reporter assays, respecitvely. |