| Cat. No. |
Product Name |
Information |
| PC-42914 |
PFK-158
PFKFB3 inhibitor
|
PFK-158 is the first potent, selective and competitive small molecule inhibitor of PFKFB3 with IC50 of 137 nM, inhibits glycolysis, induces apoptosis and autophagy. |
| PC-47499 |
Tat-NR2B9c
PSD-95 inhibitor
|
Tat-NR2B9c (NA-1) is a neuroprotective agent, exhibits high-affinity binding to the second PDZ domain of PSD-95, inhibits NR2A-NR2C/PSD-95 interactions (IC50=1-10 uM) and nNOS/PSD-95 interaction (IC50=200 nM). |
| PC-45661 |
MCB-613
SRC stimulator
|
MCB-613 is a potent steroid receptor coactivator (SRC1, SRC2 and SRC3) stimulator. |
| PC-45685 |
Emixustat hydrochloride
RPE65 inhibitor
|
Emixustat (ACU-4429) hydrochloride is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM. |
| PC-45684 |
Emixustat
RPE65 inhibitor
|
Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM. |
| PC-45670 |
BRD7552
PDX1 inducer
|
BRD7552 is a small-molecule inducer of pancreatic and duodenal homeobox 1 (PDX1) expression, induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. |
| PC-47504 |
ARA290
Erythropoietin/CD131 agonist
|
ARA290 (Cibinetide) is a non-erythropoietic erythropoietin (EPO) derivative, specific agonist of erythropoietin/CD131 heteroreceptor, improves insulin release and glucose tolerance in type 2 diabetic GK rats. |
| PC-45840 |
Azeliragon
RAGE inhibitor
|
Azeliragon (TTP488, PF-04494700) is an orally bioavailable small molecule inhibitor of RAGE, inhibits sRAGE from binding to RAGE ligands, S100b, amphoterin and carboxymethyl-lysine. |
| PC-45179 |
Deferasirox
Iron chelator
|
Deferasirox is an oral iron chelator that used to reduce chronic iron overload, also induces apoptosis in myeloid leukemia cells by targeting caspase. |
| PC-45827 |
Etomoxir
CPT-1 inhibitor
|
Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) that inhibits fatty acid β-oxidation in rat liver with IC50 of 5-20 nM. |
| PC-45142 |
Miglustat hydrochloride
Glucosylceramide synthase inhibitor
|
Miglustat hydrochloride (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase). |
| PC-45141 |
Miglustat
Glucosylceramide synthase inhibitor
|
Miglustat (N-Butyldeoxynojirimycin, SC-48334, NB-DNJ, OGT-918) is an orally active and reversible inhibitor of glucosylceramide synthase (GCS, ceramide glucosyltransferase). |
