| Cat. No. |
Product Name |
Information |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-24362 |
BMS-250
MPO inhibitor
|
BMS-250 is a potent, selective and reversible inhibitor of myeloperoxidase (MPO) with IC50 of 13 nM, Patent WO2017040449. |
| PC-24361 |
SNT-8370
VAP-1/MPO inhibitor
|
SNT-8370 is a potent, selective and irreversible dual inhibitor targeting vascular adhesion protein-1 (VAP-1) and myeloperoxidase (MPO) with IC50 of 10 nM and 17 nM respectively. |
| PC-24358 |
JM-20
Neuroprotective agent
|
JM-20 is a benzodiazepine–dihydropyridine hybrid molecule, preventsPC-12 cell death induced either by glutamate, hydrogen peroxide or KCN-mediated chemical hypoxia, a multi-target neuroprotective agent. |
| PC-24354 |
Fisetin
NUF2 inhibitor
|
Fisetin is a small molecule inhibitor of NUF2, effectively inhibits PCa cell proliferation, shows antioxidant, anticancer, neuroprotection effects. |
| PC-24321 |
SBDA
RCC2 inhibitor
|
SBDA is a small molecule inhibitor of RCC2 (TD-60) active pocket and specifically blocks RCC2 lactylation, inhibits breast cancer cell proliferation. |
| PC-24318 |
LPHN2 inhibitor D11
LPHN2 inhibitor
|
LPHN2 inhibitor D11 is a reversible and selective inhibitor of mechanosensitive GPCR latrophilin 2 (LPHN2, ADGRL2), inhibits mechanosensitivity of LPHN2 in HEK293 cells with IC50 of 20 nM. |
| PC-24316 |
Calycosin
PANoptosis inhibitor
|
Calycosin is a flavonoid compound derived from the root of Astragalus, alleviates ischemic stroke by inhibiting PANoptosis. |
| PC-24311 |
2-AAPA
Glutathione reductase inhibitor
|
2-AAPA is an irreversible inhibitor of glutathione reductase (GR) with Ki of 56 uM (yeast GR), induces ferroptosis in A549 cells, induces microtubule S-glutathionylation. |
| PC-24310 |
NFS1 inhibitor Compound 53
NFS1 inhibitor
|
NFS1 inhibitor Compound 53 is the first potent, selective inhibitor of human cysteine desulfurase (NFS1) with IC50 of 40.5 uM and Ki of 6.4 uM. |
| PC-24295 |
HOSU-53
DHODH inhibitor
|
HOSU-53 is a potent and selective inhibitor of DHODH with IC50 of 0.95 nM (hDHODH), exhibits potent antileukemic activity. |
