| Cat. No. |
Product Name |
Information |
| PC-45522 |
GBT-440
HbS polymerization inhibitor
|
GBT-440 (Voxelotor) is a new potent allosteric effector of sickle cell hemoglobin, inhibits haemoglobin S (HbS) polymerization. |
| PC-47485 |
Neuromedin N
|
A neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.. |
| PC-44669 |
Lucidin
|
Lucidin (NSC 30546) is a mutagenic substance extracted from Rubia tinctorum L., induces DNA repair synthesis in primary rat hepatocytes and transformed C3H/M2-mouse fibroblasts in culture. |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-24553 |
FGH10019
SREBP inhibitor
|
FGH10019 is a specific small molecule inhibitor of sterol regulatory element-binding protein (SREBP) with IC50 of 0.7 uM in SREBP-responsive reporter gene assays. |
| PC-24547 |
Fascin inhibitor G2
Fascin inhibitor
|
Fascin inhibitor G2 is a small molecule inhibitor of Fascin (FSCN1), inhibits the actin-bundling function of fascin with IC50 of 5-8 uM, blocks tumour invasion and metastatic colonization. |
| PC-24546 |
NP-G2-029
Fascin inhibitor
|
Fascin inhibitor G2 (NP-G2-029) is a specific small molecule inhibitor of Fascin (FSCN1) with IC50 of 0.19 uM in F-actin-bundling assay. |
