| Cat. No. |
Product Name |
Information |
| PC-60223 |
PF-DcpSi
DcpS inhibitor
|
PF-DcpSi is a potent inhibitor of the mRNA decapping scavenger enzyme (DcpS) with IC50 of 0.11 nM. |
| PC-60222 |
CK-2127107
Fast skeletal troponin activator
|
CK-2127107 (CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM. |
| PC-60193 |
2-D08
UBC9 SUMOylation inhibitor
|
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation, inhibits transcriptional expressions of SUMO1/2 and Ubc9. |
| PC-60184 |
Shield-1
FKBP ligand
|
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation. |
| PC-60177 |
CP-312
HO-1 inducer
|
CP-312 (Cardioprotectant 312) is a small molecule inducer of heme oxygenase-1 (HO-1) that protect human iPSC-derived cardiomyocytes from oxidative stress. |
| PC-60175 |
GIBH-130
|
GIBH-130 is a small molecule inhibitor of neuroinflammation, suppresses the proinflammatory cytokine production in LPS-stimulated N9 microglial cells (IC50=3.4 nM). |
| PC-60169 |
Divin
Iron chelator
|
Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells. |
| PC-60154 |
ENT1-IN-39
ENT1 inhibitor
|
ENT1-IN-39 (ENT-1 inhibitor 39) is a potent adenosine transport activity of equilibrative nucleoside transporter I protein (ENT1) with IC50 of 26.9 nM. |
| PC-70005 |
Gue-1654
OXE-R inhibitor
|
Gue-1654 (GUE 1654) is a small-molecule that inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R (Oxoeicosanoid receptor) in both recombinant and human primary cells. |
| PC-70001 |
C1632
Lin28 inhibitor
|
C1632 (Lin28-IN-1632) is a small molecule inhibitor of RNA binding protein Lin28 that blocks the Lin28/let-7 interaction, rescues let-7 processing and function in Lin28-expressing cancer cells. |
| PC-60090 |
trans-AUCB
sEH inhibitor
|
trans-AUCB is a potent, specific and orally bioavailable soluble epoxide hydrolase (sEH) inhibitor with IC50 of 1.3 nM. |
| PC-60018 |
RU.521
cGAS inhibitor
|
RU.521 (RU521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM. |
