Chemical Structure : DS-1040 tosylate hydrate
Catalog No.: PC-61011Not For Human Use, Lab Use Only.
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
DS-1040 tosylate hydrate (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa; a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile
Stroke
Phase 2 Clinical
M.Wt | 483.624 | |
Formula | C23H37N3O6S | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971.
2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081.
3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright