| Cat. No. |
Product Name |
Information |
| PC-26361 |
Ubiquinol
Antioxidant
|
Ubiquinol (Coenzyme Q10, CoQ10) is a compound thatmitochondria need to make energy, is also a strong antioxidant that protects cell membranes and keeps them stable, while helping prevent LDL cholesterol from oxidizing. |
| PC-26353 |
Rexaceract
GCase modulator
|
Rexaceract is a potent, selective positive allosteric modulator of beta-glucocerebrosidase (β-glucocerebrosidase, β-glucosidase, or GCase). |
| PC-26346 |
Obuprazine
2640663-79-0
|
Obuprazine is a small molecule G protein-coupled receptor modulator in the treatment or prevention of central nervous system diseases and/or mental diseases. |
| PC-26340 |
Mezodriton
Mitochondrial uncoupler
|
Mezodriton is a small molecule mitochondrial oxidative phosphorylation uncoupler. |
| PC-26336 |
Lomasemtiv
Troponin activator
|
Lomasemtiv is a small molecule troponin activator. |
| PC-26334 |
Linepemat
1211876-03-7
|
Linepemat is a small molecule mudulator of cortical catecholaminergic neurotransmission. |
| PC-26323 |
Dinifedriton
Mitochondrial uncoupler
|
Dinifedriton is a small molecule mitochondrial uncoupler for regulating mitochondria activity and reducing adiposity in the treatment of diseases. |
| PC-26317 |
VRK-IN-1
VRK1/VRK2 inhibitor
|
VRK-IN-1 is a potent, selective inhibitor of Vaccinia-related kinases 1 and 2 (VRK1 and VRK2) with ITC KD values of 190 nM and 401 nM, IC50 of 150 nM (VRK1). |
| PC-26316 |
VRK1 inhibitor Compound 1
VRK1 inhibitor
|
VRK1 inhibitor Compound 1 (VRK1-IN-1) is a potent, selective and ATP-competitive inhibitor of Vaccinia-related kinase 1 (VRK1) with Ki of 82 nM and IC50 of 154 nM, selective for VRK1 over VRK2. |
| PC-26308 |
GIT1/β-Pix inhibitor 14-5-18
GIT1/β-Pix inhibitor
|
GIT1/β-Pix inhibitor 14-5-18 is a small-molecule inhibitor to interrupt the protein–protein interaction (PPI) of GIT1/β-Pix complex with Ki of 1.8 uM in FP assays, directly binds to GIT1 with BLI KD of 7.7 uM, inhibits gastric cancer metastasis. |
| PC-26307 |
JX24120
MAT2B inhibitor
|
JX24120 is a specific inhibitor for methionine adenosyltransferase MAT2B, directly binds to MAT2B with SPR KD of 4.72 uM, inhibits S-adenosylmethionine (SAMe) synthesis. |
| PC-26306 |
GIT1 inhibitor Compound 3
GIT1 inhibitor
|
GIT1 inhibitor Compound 3 (GIT1-IN-C3) is a selective small molecule inhibitor of ARF GTPase protein 1 (GIT1) with MST KD of 6.2 uM, effectively disrupts GIT1 from interacting with MAT2B and RAF/MEK/ERK to halt cancer cell growth in vitro and in vivo. |
