| Cat. No. |
Product Name |
Information |
| PC-44669 |
Lucidin
|
Lucidin (NSC 30546) is a mutagenic substance extracted from Rubia tinctorum L., induces DNA repair synthesis in primary rat hepatocytes and transformed C3H/M2-mouse fibroblasts in culture. |
| PC-42293 |
EC330
LIF inhibitor
|
EC330 (EC-330, EC 330) is a first-in-class, orally bioavailable LIF (leukemia inhibitory factor) inhibitor. |
| PC-45088 |
SP-420
Iron chelating agent
|
Petadeferitrin (SP-420) is a desferrithiocin analogue and iron chelating agent that has iron-clearing efficiency with ICE value of 26.7, SP-420 is more potent than desferrithiocin. |
| PC-42072 |
BAPTA
Mg2+ chelator
|
BAPTA is a cell-permeant, calcium-specific chelator with high selectivity over Mg2+. |
| PC-45623 |
GW4869
nSMase inhibitor
|
GW-4869 (GW4869, GW 4869) is a cell-permeable, potent, specific, non-competitive inhibitor of neutral sphingomyelinase (nSMase) with IC50 of 1 uM. |
| PC-42082 |
TPEN
LIN28 inhibitor
|
TPEN (TPEDA) is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 2.5 uM, also is a specific cell-permeable heavy metal chelator. |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-26553 |
ZNF281 inhibitor ZIM
ZNF281 inhibitor
|
ZNF281 inhibitor ZIM (ZNF281 Interfering Molecule) is a specific small molecule inhibitor of transcription factor ZNF281, prevents anthracycline-mediated cardiotoxicity (AIC), enhances lung tumor regression, and prevents lung metastasis in a metastatic melanoma model. |
| PC-26552 |
BTdCPU
HRI activator
|
BTdCPU is a potent activator of heme-regulated inhibitor (HRI) eIF2α kinase that promotes eIF2α phosphorylation and induces apoptosis in Dexamethasone-resistant cancer cells. |
| PC-26548 |
SOD1 stabilizer C7
SOD1 binder
|
SOD1 stabilizer C7 is a SOD1-stabilizing small molecule preferentially bound the native-like conformation of SOD1, inhibits irreversible apo-SOD1 misfolding in vitro. |
| PC-26506 |
CCF0054500
OR2L13 agonist
|
CCF0054500 is a specific small molecule agonist of orphan GPCR OR2L13, inhibits inhibit platelet aggregation in platelet-rich plasma (PRP) with EC50 of 14 uM. |
| PC-26503 |
Z1149421873
NAP1L1 inhibitor
|
Z1149421873 (Z11) is a small-molecule inhibitor of NAP1L1 with SPR Kd value of 7.86 nM, inhibits its protein expression in vitro and exerts anti-fibrotic effects in PMCFs. |
