| Cat. No. |
Product Name |
Information |
| PC-26403 |
GPR61 inverse agonist 15
GPR61 inverse agonist
|
GPR61 inverse agonist 15 is a potent, selective, and brain-penetrant GPR61 inverse agonist with cAMP functional IC50 of 6.2 nM and 20 nM for human and mouse GPR61 respectively. |
| PC-26402 |
GPR61 inverse agonist 23
GPR61 inverse agonist
|
GPR61 inverse agonist 23 is a potent, selective, and brain-penetrant GPR61 inverse agonist with cAMP functional IC50 of 4.0 nM and 8.8 nM for human and mouse GPR61 respectively. |
| PC-26391 |
ONO-7068506
GCLC inhibitor
|
ONO-7068506 (GCLCi1) is a potent, selective glutamylcysteine ligase catalytic subunit (GCLC) inhibitor, shows potent anti-tumor effects in SMARCB1-deficient cancer cells. |
| PC-26390 |
ONO-6428513
GCLC inhibitor
|
ONO-6428513 (GCLCi0) is a potent, selective glutamylcysteine ligase catalytic subunit (GCLC) inhibitor, shows potent anti-tumor effects in SMARCB1-deficient cancer cells. |
| PC-26389 |
CZ-48
SARM1 activator
|
CZ-48 (Sulfo-ara-F-NMN) is a mimetic of nicotinamide mononucleotide (NMN) and selective cell-permeant activator of SARM1, activate SARM1 to produce cADPR from NAD, does not inhibit CD38. |
| PC-26386 |
IVMT-Rx-4
MDA-9/Syntenin inhibitor
|
IVMT-Rx-4 is a small molecule inhibitor of MDA-9/Syntenin, specifically interrupt MDA-9/Syntenin signaling, leading to an inhibition in progression of PC cells to bone metastasis. |
| PC-26378 |
Z-5891
COPS3 inhibitor
|
Z-5891 is a highly selective COPS3 inhibitor, exhibits concentration-dependent proliferation-inhibitory activity against 143B cells with IC50 of 3.28 uM. |
| PC-26377 |
NBDHEX
GST inhibitor
|
NBDHEX is a potent glutathione S-transferase (GST) inhibitor, inhibits human glutathione S-transferases GSTA1-1, GSTP1-1 and GSTM2-2 with IC50 of 25 uM, 0.8 uM and <0.01 uM, is cytotoxic toward P-glycoprotein-overexpressing tumor cell lines. |
| PC-26374 |
Aflatoxin B1
1162-65-8
|
Aflatoxin B1 (AFB1) is a Group 1A carcinogen and a secondary metabolite produced by Aspergillus flavus and A. parasiticus, can induces mutations by causing a G to T transversion at the third nucleotide of codon 249 in the tumor suppressor gene p53. |
| PC-26371 |
OXGR1 agonist A-1
OXGR1 agonist
|
OXGR1 agonist A-1 is a potent and selective OXGR1 (Oxoglutarate Receptor 1, GPR99) agonist, activates Gq signaling of OXGR1 with EC50 of 626.5 nM. |
| PC-26361 |
Ubiquinol
Antioxidant
|
Ubiquinol (Coenzyme Q10, CoQ10) is a compound thatmitochondria need to make energy, is also a strong antioxidant that protects cell membranes and keeps them stable, while helping prevent LDL cholesterol from oxidizing. |
| PC-26353 |
Rexaceract
GCase modulator
|
Rexaceract is a potent, selective positive allosteric modulator of beta-glucocerebrosidase (β-glucocerebrosidase, β-glucosidase, or GCase). |
