| Cat. No. |
Product Name |
Information |
| PC-22693 |
DS08701581
FER kinase inhibitor
|
DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy. |
| PC-22686 |
NSI-189 phosphate
Neurogenic compound
|
NSI-189 phosphate is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
| PC-22685 |
NSI-189
Neurogenic compound
|
NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo. |
| PC-22683 |
FR900359
pan-Gq inhibitor
|
FR900359 is a plant-derived depsipeptide and specific pan-Gq (Gq/11/14) inhibitor, selectively inhibits Gq-dependent signalling, with little effect on Galphasbetagamma, Galphaibetagamma, or Galpha12/13betagamma heterotrimer activity. |
| PC-22682 |
Hymeglusin
HMGCS1 inhibitor
|
Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity. |
| PC-22678 |
DS28120313
Hepcidin inhibitor
|
DS28120313 is a potent orally active hepcidin production inhibitor with IC50 of 93 nM (hepcidin mRNA expression), shows serum hepcidin-lowering effects. |
| PC-22671 |
GFRα2/GFRα23 inhibitor 16
GFRα2/3 inhibitor
|
GFRα2/GFRα23 inhibitor 16 is a selective small moelcule inhibitor of glycosylphosphatidylinositol-anchored co-receptor GFRa2/GFRa3 with IC50 of 0.1/0.2 uM respectively, selective over RET. |
| PC-22666 |
Myeloperoxidase inhibitor RL6
Myeloperoxidase inhibitor
|
Myeloperoxidase inhibitor RL6 is a potent, reversible inhibitor of myeloperoxidase (MPO) and hypochlorous acid (HOCl) scavenger, inhibits neutrophil extracellular trap release (NETosis). |
| PC-22644 |
TAK-683
KISS1R agonist
|
TAK-683 is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay. |
| PC-22643 |
TAK-683 acetate
KISS1R agonist
|
TAK-683 acetate is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay. |
| PC-22642 |
TAK-448 acetate
KISS1R agonist
|
TAK-448 (MVT-602) acetate is a potent and full KISS1R (metastin receptor) agonist and kisspeptin analogue with IC50 of 3 pM in radioimmunoassay. |
| PC-22640 |
(S)-PHA533533
Ube3a unsilencer
|
(S)-PHA533533 is a potent, small molecule unsilencer of paternal UBE3A in mouse primary neurons with EC50 of 0.54 uM, Emax=80%, effectively downregulates Ube3a-ATS/UBE3A ATS and epigenetically unsilences paternal Ube3a/UBE3A in both mouse and human neuron. |
