| Cat. No. |
Product Name |
Information |
| PC-22368 |
7-alpha-hydroxycholesterol
TCR inhibitor
|
7alpha-hydroxycholesterol (7a-HC) is the 7alpha-hydroxy derivative of cholesterol, is a potent inhibitor of TCR signaling and promotes membrane binding of CD3ε cytoplasmic domain. |
| PC-22367 |
SHP1705
Cryptochrome stabilizer
|
SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice. |
| PC-22352 |
Rotenone
Complex I inhibitor
|
Rotenone is a mitochondrial electron transport chain complex I inhibitor, induces apoptosis through enhancing mitochondrial reactive oxygen species production. |
| PC-22351 |
DPPC
|
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes, DPPC is the main lipid component of pulmonary surfactant. |
| PC-22340 |
QDPR inhibitor 9b
QDPR inhibitor
|
QDPR inhibitor 9b is a small molecule inhibitor of quinonoid dihydropteridine reductase (QDPR) with IC50 of 0.72 uM. |
| PC-22338 |
STL427944
FOXM1 inhibitor
|
STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes. |
| PC-22336 |
ARN16186
NAAA inhibitor
|
ARN16186 is a potent, specific small molecule inhibitor of N-Acylethanolamine-hydrolyzing acid amidase (NAAA) with IC50 of 23 nM. |
| PC-22333 |
ML257
ABHD10 inhibitor
|
ML257 (ABL303) is a selective inhibitor of α,β-hydrolase domain-containing 10 (ABHD10) with IC50 of 21 nM, >59-fold selectivity over 40+ other serine hydrolases. |
| PC-22326 |
E745-0011
TIPE3 inhibitor
|
E745-0011 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities. |
| PC-22325 |
K784-8160
TIPE3 inhibitor
|
K784-8160 is a small molecule inhibitor of tumor necrosis factor-α-induced protein 8-like 3 (TNFAIP8L3, TIPE3), exhibits potent anti-tumor activities. |
| PC-22324 |
OR51E2 antagonist C80
OR51E2 inhibitor
|
OR51E2 antagonist C80 (Compound 80) is an allosteric antagonist and inverse agonist of olfactory receptor OR51E2 with IC50 of 5.2 uM, acts as a negative allosteric modulator (NAM) by significantly decreasing the agonist efficacy. |
| PC-22305 |
JYQ-164
DJ-1/PARK7 inhibitor
|
JYQ-164 (JYQ164) is a potent, highly selective Parkinson disease protein 7 (PARK7/DJ-1) inhibitor with IC50 of 21 nM, binds covalently and selectively to PARK7 Cys106. |
