| Cat. No. |
Product Name |
Information |
| PC-20301 |
RF03176
AQP9 inhibitor
|
RF03176 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability). |
| PC-20300 |
TGN-020
AQP4 inhibitor
|
TGN-020 (TGN020) is a potent, selective aquaporin 4 (AQP4) inhibitor with IC50 of 3 uM. |
| PC-20274 |
SPT inhibitor compound-2
SPT inhibitor
|
SPT inhibitor compound-2 is a potent, orally active serine palmitoyltransferase (SPT) inhibitor with IXC50 of 0.51 nM in cell-free assays. |
| PC-20264 |
Indoluidin E
DHODH inhibitor
|
Indoluidin E is an indoluidin D derivative, and potent selective dihydroorotate dehydrogenase (DHODH) inhibitor, suppresses cancer cell growth. |
| PC-20263 |
Indoluidin D
DHODH inhibitor
|
Indoluidin D is a potent selective dihydroorotate dehydrogenase (DHODH) inhibitor, promotes myeloid differentiation and inhibits the proliferation of acute promyelocytic leukemia HL-60 cells. |
| PC-20258 |
Dichloroallyl lawsone
DHODH inhibitor
|
Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC-126771) is a synthetic analogue of the antimalarial lapachol, inhibits mitochondrial dihydroorotate dehydrogenase (DHODH) with antineoplastic activity. |
| PC-20224 |
Compound 30666
IgH gene enhancer inhibitor
|
Compound 30666 is a specific small molecule inhibitor of IgH enhancer transcriptional activity with IC50 of 2.1 uM, inhibits immunoglobulin production by MM cells. |
| PC-20214 |
MIF2 inhibitor 5d
MIF-2 inhibitor
|
MIF2 inhibitor 5d is a selective inhibitor of d-dopachrome tautomerase (d-DT or MIF2) with IC50 of 1.0 μM for MIF2 tautomerase activity and a high selectivity over MIF. |
| PC-20213 |
2,5-pyridinedicarboxylic acid
MIF2 inhibitor
|
2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74. |
| PC-20196 |
ψTnI
cTnI/PKCδ inhibitor
|
ψTnI (Peptide DWRKNIDA) is a selective, high-affinity, eight amino acid peptide inhibitor of cardiac troponin I (cTnI), directly binds to δPKC with high affinity (Kd=5 nM) and inhibits cTnI/δPKC interaction. |
| PC-20166 |
TMX-4084
PIP4K2C binder
|
TMX-4084 (TMX4084) is a highly potent, selective PIP4K2C binder with KD of 7.3 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
| PC-20165 |
TMX-4102
PIP4K2C binder
|
TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM). |
