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Cat. No. Product Name Information
PC-25171

Cyanabactin

ABA receptor agonist

Cyanabactin is a potent and selective plant hormone abscisic acid (ABA) receptor agonist that preferentially activates Pyrabactin Resistance 1 (PYR1) with low nanomolar potency, exhihibits a wide spectrum of ABA-like activities.
PC-25170

ABA receptor agonist iCB

ABA receptor agonist

ABA receptor agonist iCB is a novel synthetic abscisic acid (ABA) receptor agonist with broad-spectrum activation across the three receptor subtypes, has IC50 of 0.16 uM in seedling establishment inhibition assay.
PC-25146

BI033

BACH1 inhibitor

BI033 is a selective small-molecule BTB and CNC homology 1 (BACH1) inhibitor, specifically binds to BACH1 WT with Kd of 9.0 uM, significantly upregulates HO-1 mRNA and protein expression.
PC-25137

GI-Y1

GSDMD inhibitor

GSDMD inhibitor Y1 (GI-Y1) is a selective gasdermin D (GSDMD) inhibitor, binds to GSDMD with SPR KD of 7.69 uM, shows cardioprotective effects.
PC-25115

M6766

ERO1α inhibitor

M6766 is a potent, selective inhibitor of endoplasmic reticulum oxidoreductase 1α (ERO1α) with IC50 of 1.4 uM and KD of 1.1 uM.
PC-25105

DEL-S1

SLIT2/ROBO1 inhibitor

DEL-S1 is a first-in-class small molecule that binds to SLIT2 and disrupts its interaction with ROBO1 with IC50 of 68.8 uM in TR-FRET assays.
PC-25037

BMN 349

Z α1-antitrypsin polymerisation inhibitor

BMN 349 (Crovozalpon, BMN349) is a specific small molecule inhibitor of Z mutant alpha-1 antitrypsin (Z-AAT) polymerization that preferentially binds Z-AAT and blocks polymerization.
PC-25013

TREM2 agonist C1

TREM2 agonist

TREM2 agonist C1 is a structural analog of VG-3927 and small molecule agonist of triggering receptor expressed on myeloid cells 2 (TREM2) with KD of 71.36 uM in MST assays.
PC-25011

YT-II-100

CPSF3 inhibitor

YT-II-100 is a novel small molecule inhibitor of Cleavage and Polyadenylation Specific Factor 3 (CPSF3), increases the global abundance of R-loops.
PC-24839

NGI-186

Oligosaccharyltransferase inhibitor

NGI-186 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.06 uM.
PC-24838

NGI-190

Oligosaccharyltransferase inhibitor

NGI-190 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.59 uM.
PC-24837

NGI-189

Oligosaccharyltransferase inhibitor

NGI-189 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.09 uM.

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