You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets

Request The Product List ofOther Targets Other Targets

Cat. No. Product Name Information
PC-47110

MS0015203

GPR171 agonist

MS0015203 (MS15203) is a potent, selective small-molecule agonist of neuropeptide receptor GPR171 with binding IC50 of 81 nM (WT GPR171).
PC-47092

RG100204

AQP9 inhibitor

RG100204 is a novel selective, small molecule inhibitor of the neutral solute channel Aquaporin 9 (AQP9), inhibits AQP9 water permeability (IC50=110 nM) and AQP9 glycerol permeability (IC50=76 nM).
PC-47091

UNC5452

Nek1 inhibitor

UNC5452 is a selective NIMA-related kinase 1 (Nek1) inhibitor with IC50 of 4.3 uM.
PC-47087

IL-17A PPIm 23

IL-17A modulator

IL-17A PPIm 23 is a potent, orally bioavailable, small-molecule protein-protein interaction modulator (PPIm) of IL-17A, shows potential treatment of psoriasis and other inflammatory diseases.
PC-47085

RG3039

DcpS inhibitor

RG3039 (PF-06687859) is a potent, orally bioavailable and brain-penetrant inhibitor of the ribonucleic acid scavenger enzyme DcpS with IC50 of 3.4 nM.
PC-47083

TH10785

OGG1 activator

TH10785 is a small-molecule activator of 8-oxoguanine (8-oxoG) DNA glycosylase 1 (OGG1), increases the enzyme activity 10-fold, TH10785 increases OGG1 recruitment to and repair of oxidative DNA damage in cells.
PC-47075

GBT1118

Hemoglobin modifier

GBT1118 is a potent, orally bioavailable allosteric modifier of hemoglobin O2 affinity, binds covalently and reversibly via an imine intermediate to the NH2-terminal valine of the Hb α-chain.
PC-47074

RPI-194

Troponin activator

RPI-194 is a novel troponin activator that binds to cardiac/slow skeletal muscle troponin, binds to cardiac troponin with KD of 24 uM, stabilizing the activated complex between troponin C and the switch region of troponin I.
PC-47073

cjoc42

Gankyrin inhibitor

cjoc42 is a specific small molecule that is capable of binding to gankyrin (ITC Kd=580 nM), inhibit gankyrin activity in a dose-dependent manner.
PC-47071

Carmofur

ASAH1 inhibitor

Carmofur (HCFU) is a pyrimidine analogue with antineoplastic activity, Carmofur is a highly potent acid ceramidase (ASAH1) inhibitor with IC50 of 29 nM (rat recombinant ASAH1).
PC-47066

UNC7938

Endosomolytic compound

UNC7938 (UNC10217938 ) is a small molecule that enhance the escape of oligonucleotides from intracellular membrane compartments, enhance the delivery of oligonucleotides.
PC-47060

GNF-9228

β-cell proliferation activator

GNF-9228 is a small molecule that stimulates human β-cell proliferation, selectively activates human β-cell relative to α- or δ-cell proliferation.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com