| Cat. No. |
Product Name |
Information |
| PC-61340 |
PF-06928215
cGAS inhibitor
|
PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM. |
| PC-61320 |
RK-33
|
RK-33 is a first-in-class small molecule inhibitor of RNA helicase DDX3, binds specifically to DDX3, but not to the closely related proteins DDX5 and DDX17. |
| PC-61316 |
Teglicar
|
Teglicar (ST-1326) is a potent, selective and reversible inhibitor of liver carnitine palmitoyl-transferase 1 (L-CPT1) with IC50 of 0.68 uM, Ki of 0.36 uM. |
| PC-61262 |
TB-03
Grb2 SH2 inhibitor
|
TB-03 is a small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774). |
| PC-61245 |
DC_AC50
|
DC_AC50 (DCAC50) is a small molecule that inhibits the human copper chaperones Atox1 and CCS (Kd=6.8 and 8.2 uM), blocks copper trafficking and significantly attenuates cancer cell proliferation. |
| PC-61244 |
STOML3 inhibitor OB-1
|
STOML3 inhibitor OB-1 is a small-molecule inhibitor of STOML3 oligomerization that reverses pathological mechanical hypersensitivity in vivo. |
| PC-61243 |
r(GGGGCC)n binder 1a
|
A bioactive, specific small molecule that targets RNA of the expanded repeat (r(GGGGCC)exp) with Kd of 9.7 uM. |
| PC-61242 |
UNC-3230
|
UNC-3230 (UNC3230) is a selective, small molecule inhibitor of PIP5K1C with IC50 of 41 nM, does not ihibits other lipid kinases including PI3Ks. |
| PC-61241 |
SPRi3
|
SPRi3 (SPR inhibitor 3) is a small molecule inhibitor of sepiapterin reductase (SPR) with IC50 of 74 nM in cell-free assays, efficiently reduces biopterin levels with IC50 of 5.2 uM. |
| PC-61236 |
AGI-1067
|
AGI-1067 (Succinobucol) is a potent inhibitor of TNF-α-inducible expression of VCAM-1, MCP-1 and E-selectin (IC50=6,10 and 25 uM) with concurrent antioxidant and lipid-modulating properties. |
| PC-61214 |
Pyrimidinone 8
|
Pyrimidinone 8 is a novel allosteric, non-competitive divalent metal transporter-1 (SLC11A2/DMT1) inhibitor with Ki of 20 uM. |
| PC-61208 |
Ferristatin II
Iron transport inhibitor
|
Ferristatin II (NSC 8679, NSC8679, Chlorazol Black) is a small molecule iron transport inhibitor that promotes degradation of transferrin receptor-1 in vitro and in vivo, through a nystatin-sensitive lipid raft pathway. |
