| Cat. No. |
Product Name |
Information |
| PC-72515 |
ELOVL1-IN-22
ELOVL1 inhibitor
|
ELOVL1-IN-22 is a potent, selective, CNS-penetran inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme, reduces C26:0 VLCFA synthesis in HEK293 with EC50 of 0.4 nM. |
| PC-72504 |
ARSA-IN-1r
ARSA inhibitor
|
ARSA-IN-1r (ARSAi) is the first reversible inhibitor of human Arylsulfatase A (ARSA) with SPR KD of 21 uM and IC50 of 13.2 uM. |
| PC-72501 |
JH-RE-06
REV1-REV7 inhibitor
|
JH-RE-06 is a potent REV1-REV7 interface inhibitor (IC50=0.78 uM, Kd=0.42 uM) that disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ, induces REV1 dimerization and blocks POLζ recruitment. |
| PC-72498 |
Macrocyclic peptide D4-2
CD47-SIRPα inhibitor
|
Macrocyclic peptide D4-2 is a macrocyclic peptide consisting of 15 amino acids that binds to the ectodomain of mouse SIRPα (Kd=10 nM, IgV-B6 SIRPα) and efficiently blocks CD47-SIRPα interaction in an allosteric manner (IC50=0.18 uM). |
| PC-72492 |
SU056
YBX1 inhibitor
|
SU056 (SU-056) is a specific small molecule that potently inhibits tumor growth and progression via Y box binding protein 1 (YBX1, YB1) inhibition. |
| PC-72477 |
CPSF3 inhibitor 2
CPSF3 inhibitor
|
CPSF3 inhibitor 2 is a small moleculemodulator of pre-mRNA processing, targets and binds to human CPSF3 (Kd=370 nM). |
| PC-72476 |
JTE-607
CPSF3 inhibitor
|
JTE-607 (JTE607) is a multiple cytokine inhibitor that potently suppresses production of proinflammatory cytokines, targets pre-messenger RNA endonuclease cleavage and polyadenylation specificity factor 3 (CPSF3). |
| PC-72465 |
I-OMe-AG-538
PI5P4Kα inhibitor
|
I-OMe-AG-538 (I-OMe-Tyrphostin AG 538) is an ATP-competitive inhibitor of PI5P4Kα with an IC50 of 1 uM, also inhibits the PIP4K2A activity with IC50 of 2.1 uM. |
| PC-72464 |
PIP4K-IN-a131
PIP4K inhibitor
|
PIP4K-IN-a131 (PIP4K inhibitor a131) is a PIP4K lipid kinase inhibitor with IC50 of 1.9 uM (PI5P4Kα), selectively kills cancer cells, while protecting normal cells. |
| PC-72463 |
BAY-091
PIP4K2A inhibitor
|
BAY-091 (BAY091) is a potent and highly selective inhibitor of PIP4K2A with IC50 of 16 nM in the high ATP (2 mM) HTRF assay. |
| PC-72461 |
MLS000544460
EYA2 inhibitor
|
MLS000544460 (EYA2i) is a specific, allosteric inhibitor of Eya2 phosphatase with IC50 of 4.1 uM, KD of 2.0 uM, does not bind Eya3 ED, Eya1 and Eya4 ED. |
| PC-72458 |
JumOCA peptide
OCA-B peptide inhibitor
|
JumOCA peptide (VKELLRRKRGH) is a peptide corresponding to the transcriptional coregulator OCA-B N terminus, membrane-penetrating OCA-B peptide inhibitor. |
