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Cat. No. Product Name Information
PC-70335

TRAF-STOP 6877002

CD40-TRAF6 inhibitor

TRAF-STOP 6877002 (SMI-6877002) is a small molecule inhibitor that blocks the interaction between CD40 and TRAF6 (TRAF-STOP), while leaving CD40-TRAF2/3/5 interactions intact, thereby preserving CD40-mediated immunity.
PC-70334

SC57461A

LTA4H inhibitor

SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM.
PC-70333

ARM-1

LTA4H inhibitor

ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
PC-70326

Seriniquinone

Dermcidin inhibitor

Seriniquinone (S 747855) is a melanoma-selective anticancer agent (IC50=30 nM, Malme-3M cell line), induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin.
PC-70315

Endosidin 2

Endosomal trafficking inhibitor

Endosidin 2 (Endosidin2, ES2) is a small molecule binds to the EXO70 (exocyst component of 70 kDa) subunit of the exocyst complex (Kd=253 uM), resulting in inhibition of exocytosis and endosomal recycling in both plant and human cells and enhancement of plant vacuolar trafficking.
PC-70314

SI-2 hydrochloride

SRC-3 inhibitor

A potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
PC-70313

SI-2

SRC-3 inhibitor

SI-2 (EPH-116) is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
PC-70287

PDZ1i

MDA-9/Syntenin inhibitor

PDZ1i (113B7) is a specific inhibitor of MDA-9/Syntenin activity that inhibits MDA-9/Syntenin binding to EGFRvIII.
PC-70286

FD-44

FD-44 (FD44, NCS-1-Ric8a inhibitor FD44) is a potent inhibitor of the NCS-1/Ric8a interaction, interferes with NCS-1/Ric8a binding, and restores normal synapse number and associative learning in a Drosophila FXS model.
PC-70281

CBR-096-4

CBR-096-4 is a derivative of the antifungal drug itraconazole (ITA) as an inhibitor of MFB cell fate in resident fibroblasts derived from multiple murine and human tissues.
PC-61205

XEN 602

DMT1 inhibitor

XEN 602 (XEN602) is a potent, specific divalent metal transporter 1 (DMT1) inhibitor that inhibits Mn incorporation in HEK293 cells with IC50 of 0.3 nM.
PC-61196

FPH1

iPS differentiation inducer

FPH1 (BRD6125) is a small molecule that induces functional proliferation of hepatocytes in vitro, increases expansion of primary human hepatocytes and induces maturation of hepatocyte-like cells (iHeps).

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