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Fhit-IN-15

Chemical Structure : Fhit-IN-15

CAS No.: 683784-49-8

Fhit-IN-15 (Fhit inhibitor 15)

Catalog No.: PC-61689Not For Human Use, Lab Use Only.

Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.

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    Biological Activity

    Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells.

    Physicochemical Properties

    M.Wt 434.333
    Formula C24H20BrNO2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    10-(4-bromophenyl)-7,7-dimethyl-6,7,8,10-tetrahydro-5H-indeno[1,2-b]quinoline-9,11-dione

    References

    1. Lange S, et al. Chembiochem. 2017 Sep 5;18(17):1707-1711.

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