| Cat. No. |
Product Name |
Information |
| PC-49632 |
BI-0955
HSD17B13 inhibitor
|
BI-0955 is an inactive HSD17B13 control compound for BI-3231. |
| PC-49630 |
Levetiracetam
SV2A ligand
|
Levetiracetam (UCB L059) an antiepileptic drug with a unique activity profile in animal models of seizure and epilepsy, binds to (pKi=5.2) and modulates synaptic vesicle protein SV2A. |
| PC-49628 |
PKR inhibitor C16
PKR inhibitor
|
PKR inhibitor C16 (GW506033X) is a specific small molecule inhibitor of double-stranded RNA-dependent protein kinase (PKR). |
| PC-49621 |
JYQ-88
PARK7 (DJ-1) inhibitor
|
JYQ-88 is a potent, selective and covalent PARK7 inhibitor with IC50 of 0.13 uM in DiFMUAc assays, 100-fold selectivity over UCHL1 (PARK5, IC50=11.1 uM), covalently modifies the active site Cys106. |
| PC-49607 |
NCP26
ProRS inhibitor
|
NCP26 is a potent, ATP-competitive prolyl-tRNA synthetase (ProRS, PRS) inhibitor, inhibits recombinant human ProRS in the presence of 100 μM proline with KD of 0.35 nM in TR-FRET assays. |
| PC-49591 |
DDIT
Hyaluronan synthase inhibitor
|
DDIT is a potent, non-toxic inhibitor of hyaluronan synthesis via targeting hyaluronan synthase (HAS), significantly suppresses the aggressiveness of triple-negative breast cancer cells grown in tissue culture. |
| PC-49589 |
ARUK2001607
PI5P4Kγ inhibitor
|
ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+). |
| PC-49562 |
F12511
ACAT inhibitor
|
Eflucimibe (F12511) is a highly potent, selective inhibitor of acyl-CoA: cholesterol acyltransferase ( ACAT/SOAT) with IC50 of 3, 7, and 71 nM in whole cell assays using HepG2, CaCo-2 and THP-1 cell lines, respectively. |
| PC-49561 |
NTE-122
ACAT inhibitor
|
NTE-122 (NTE122) is a potent selective and competitive acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, inhibits microsomal ACAT activities of various tissues and cultured cells (HepG2 and CaCo-2), with IC50 values from 1.2 to 9.6 nM. |
| PC-49557 |
FR054
PGM3 inhibitor
|
FR054 (FR-054) is a specific small molecule inhibitor of hexosamine biosynthetic pathway (HBP) enzyme N-Acetylglucosamine-phosphate Mutase (PGM3), shows a remarkable anti-breast cancer effect. |
| PC-49548 |
DS55980254
PTDSS1 inhibitor
|
DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2. |
| PC-49527 |
SEN177
Glutaminyl cyclase inhibitor
|
SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM. |
