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Cat. No. Product Name Information
PC-49591

DDIT

Hyaluronan synthase inhibitor

DDIT is a potent, non-toxic inhibitor of hyaluronan synthesis via targeting hyaluronan synthase (HAS), significantly suppresses the aggressiveness of triple-negative breast cancer cells grown in tissue culture.
PC-49589

ARUK2001607

PI5P4Kγ inhibitor

ARUK2001607 is a potent, selective and brain penetrant PI5P4Kγ inhibitor with binding KD of 7.1 nM, pIC50 of 7.1 (PI5P4Kγ+).
PC-49562

F12511

ACAT inhibitor

Eflucimibe (F12511) is a highly potent, selective inhibitor of acyl-CoA: cholesterol acyltransferase ( ACAT/SOAT) with IC50 of 3, 7, and 71 nM in whole cell assays using HepG2, CaCo-2 and THP-1 cell lines, respectively.
PC-49561

NTE-122

ACAT inhibitor

NTE-122 (NTE122) is a potent selective and competitive acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, inhibits microsomal ACAT activities of various tissues and cultured cells (HepG2 and CaCo-2), with IC50 values from 1.2 to 9.6 nM.
PC-49557

FR054

PGM3 inhibitor

FR054 (FR-054) is a specific small molecule inhibitor of hexosamine biosynthetic pathway (HBP) enzyme N-Acetylglucosamine-phosphate Mutase (PGM3), shows a remarkable anti-breast cancer effect.
PC-49548

DS55980254

PTDSS1 inhibitor

DS55980254 (DS 55980254) is potent, selective and orally active PTDSS1 (phosphatidylserine synthetase 1) inhibitor, suppresses phosphatidylserine (PS) production activity of PTDSS1 (IC50=100 nM) in cell-free assays, but not that of PTDSS2.
PC-49527

SEN177

Glutaminyl cyclase inhibitor

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
PC-49511

Tryptolinamide

PFK1 inhibitor

Tryptolinamide (TLAM) is a small-molecule compound that activates mitochondrial respiration in cybrids generated from patient-derived mitochondria and fibroblasts from patient-derived iPSCs, inhibits phosphofructokinase-1 (PFK1) with an ATP-uncompetitive and F6P-competitive manner (Ki=5.0 uM).
PC-49503

LMTK3 inhibitor C36

LMTK3 inhibitor

LMTK3 inhibitor C36 is a highly selective, ATP-competitive inhibitor of lemur tyrosine kinase 3 (LMTK3) with IC50 of 100 nM in in vitro kinase assays and MST binding Kd of 1.87 uM.
PC-49470

MO-I-1182

ASPH inhibitor

MO-I-1182 is a small molecule inhibitor of aspartate beta-hydroxylase (ASPH), suppresses cholangiocarcinoma metastasis.
PC-49460

CLOCK inhibitor CLK8

CLOCK inhibitor

CLOCK inhibitor CLK8 is a CLOCK-binding small molecule disrupting the interaction between CLOCK and BMAL1, interferes with nuclear translocation of CLOCK both in vivo and in vitro.
PC-49459

TH301

CRY2 stabilizer

TH301 (TH 301) is a isoform-selective small molecule stabilizer of Cryptochrome 2 (CRY2).

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