Dichloroallyl lawsone | DHODH inhibitor

Chemical Structure : Dichloroallyl lawsone

Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC 126771)

Catalog No.: PC-20258Not For Human Use, Lab Use Only.

Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC-126771) is a synthetic analogue of the antimalarial lapachol, inhibits mitochondrial dihydroorotate dehydrogenase (DHODH) with antineoplastic activity.

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Biological Activity

Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC-126771) is a synthetic analogue of the antimalarial lapachol, inhibits mitochondrial dihydroorotate dehydrogenase (DHODH) with antineoplastic activity.

Physicochemical Properties

M.Wt	283.10
Formula	C13H8Cl2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(3,3-dichloroprop-2-enyl)-4-hydroxynaphthalene-1,2-dione

References

1. Baldwin J, et al. J Biol Chem. 2002 Nov 1;277(44):41827-34.

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Dichloroallyl lawsone (Dichlorolapachol, DCL, NSC 126771)

Biological Activity

Physicochemical Properties

References

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