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RF03176

Chemical Structure : RF03176

CAS No.: 685123-50-6

RF03176 (RF 03176)

Catalog No.: PC-20301Not For Human Use, Lab Use Only.

RF03176 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    RF03176 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.3 uM (inhibition of CHO-AQP9 cell water permeability).
    RF03176 shows little to no activity against AQP3, AQP7, and AQP8.

    Physicochemical Properties

    M.Wt 270.31
    Formula C13H10N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(benzo[d][1,2,3]thiadiazol-6-yl)-3-phenylurea

    References

    1. Sabina Jelen, et al. J Biol Chem. 2011 Dec 30;286(52):44319-25.

    2. Sören J Wacker, et al. Mol Membr Biol. 2013 May;30(3):246-60.

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