| Cat. No. |
Product Name |
Information |
| PC-35917 |
hClpP activator D9
hClpP activator
|
hClpP activator D9 is a potent and species-selective activator of human ClpP (hClpP, human Caseinolytic protease P) by mimicking the natural chaperone ClpX.. |
| PC-35895 |
PXS-5153A
LOXL2/LOXL3 inhibitor
|
PXS-5153A (PXS5153A) is a potent, selective, fast-acting, dual LOXL2/LOXL3 inhibitor with IC50 of <40 nM against all mammalian species LOXL2, inhibits human LOXL3 with IC50 of 63 nM. |
| PC-35891 |
NCGC00135472
DRV1/GPR32 agonist
|
DRV1 (GPR32) agonist C2A (NCGC00135472) is a synthetic molecule that activate human resolvin D1 receptor DRV1/GPR32 receptor with EC50 of 0.37 uM and 0.05 uM in β-arrestin and cAMP assays, respectively. |
| PC-35888 |
BDP-NAC
|
BDP-NAC is a novel persulfide donor that shows selectivity towards H2 O2 over other potential oxidative or nucleophilic triggers, resulting in the sustained release of the persulfide of N-acetyl cysteine (NAC). |
| PC-35883 |
Sphynolactone-7
|
Sphynolactone-7 (SPL7) is a potent, specific, femtomolar-range suicide germination stimulant for the parasitic plant Striga hermonthica with minimum effective concentration (MEC) of 10 fM that produces any seed germination. |
| PC-35874 |
Pin1 inhibitor API-1
Pin1 inhibitor
|
Pin1 inhibitor API-1 (API-1) is a potent, specific inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) and inhibits Pin1 cis-trans isomerizing activity with IC50 of 72.3 nM. |
| PC-35864 |
CSRM617
ONECUT2 inhibitor
|
CSRM617 (CSRM-617) is a small-molecule inhibitor of the transcription factor ONECUT2 (OC2) with Kd of 7.43 uM in SPR assays, binds to OC2-HOX domain directly. |
| PC-35860 |
AP1867-2-(carboxymethoxy)
FKBP12 ligand
|
AP1867-2-(carboxymethoxy) is a ligand of FKBP12, binds to CRBN ligand via a linker to form dTAG molecules. |
| PC-35857 |
ARN14494
Serine palmitoyltransferase inhibitor
|
ARN14494 (ARN-14494) is a potent, small molecule serine palmitoyltransferase (SPT) inhibitor with IC50 of 27.3 nM. |
| PC-35852 |
SGC-GAK-1
GAK inhibitor
|
SGC-GAK-1 (GAK inhibitor 1) is a potent, selective, and cell-active inhibitor of cyclin G-associated kinase (GAK) with Ki of 3.2 nM, 16,000-fold selectivity over NAK. |
| PC-35840 |
AB-680
CD73 inhibitor
|
AB-680 (Quemliclustat) is a highly potent, selective, reversible inhibitor of CD73 with Ki/IC50 of 4.9/70 pM (hCD73). |
| PC-35831 |
PZ-2891
PANK modulator
|
PZ-2891 (PZ2891) a specific, allosteric, BBB-permeable, orally active Pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM, hPANK3) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA in biochemical assays. |
