| Cat. No. |
Product Name |
Information |
| PC-35371 |
Edonerpic maleate
CRMP2 inhibitor, Aβ inhibitor
|
Edonerpic maleate (T-817MA) is a neurotrophic agent that can protects neuronal cells and modifies their morphology, binds to collapsin-response-mediator-protein 2 (CRMP2) and inhibits amyloid-β peptides (Aβ). |
| PC-35366 |
Lipofermata
Fatty acid transport inhibitor
|
Lipofermata (CB16.2 aka) is a specific fatty acid transport (FATP) inhibitor, blocks human FATP2-mediated fatty acid uptake (IC50=4.84 uM in Caco-2 cells) without impacting other cellular functions. |
| PC-35343 |
5MPN
PFKFB4 inhibitor
|
PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3. |
| PC-35335 |
CPSI-1306
MIF inhibitor
|
CPSI-1306 (CPSI1306) is an orally available small-molecule MIF antagonist, protects against UVB-induced squamous cell carcinoma, reduces the severity of animal model of multiple sclerosis. |
| PC-35333 |
EC359
LIFR inhibitor
|
EC359 (EC-359) is a first-in-class, orally available inhibitor of leukemia inhibitory factor (LIF), blocks LIF-LIFR interaction and binds to LIFR with affinity of 81 nM in SPR assay. |
| PC-35330 |
CCG-222740
MRTF/SRF inhibitor
|
CCG-222740 (CCG222740) is a pharmacological inhibitor of MRTF/SRF signalling, shows greater inhibitory effect on MRTF/SRF target genes than MRTF-A inhibitor CCG-203971, with IC50 of 5 uM in fibroblast-mediated collagen contraction assay. |
| PC-35314 |
S-230
OXE receptor antagonist
|
OXE-R antagonist S-230 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor) with IC50 of 0.12 nM, inhibits 5-oxo-ETE-induced calcium mobilization in human neutrophils. |
| PC-35313 |
S-C025
OXE receptor antagonist
|
S-C025 is a highly potent antagonist of oxoeicosanoid receptor (OXE receptor, OXE-R) with IC50 of 0.12 nM. |
| PC-35242 |
Z-590
MIF inhibitor
|
Z-590 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity. |
| PC-35241 |
ISO-92
MIF inhibitor
|
ISO-92 is a potent inhibitor of macrophage migration inhibitory factor (MIF) tautomerase activity with IC50 of 0.55 uM. |
| PC-35239 |
TES-1025
ACMSD inhibitor
|
TES-1025 (TES1025) is a potent, selective inhibitor of human ACMSD (α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase) with IC50 of 13 nM, increases NAD+ levels in cellular systems. |
| PC-35233 |
SAN9812
|
SAN9812 (Carnostatine) is a potent, highly selective, competitive inhibitor of Carnosinase 1 (CN1) activity with Ki of 11 nM. |
