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Cat. No. Product Name Information
PC-60175

GIBH-130

GIBH-130 is a small molecule inhibitor of neuroinflammation, suppresses the proinflammatory cytokine production in LPS-stimulated N9 microglial cells (IC50=3.4 nM).
PC-60169

Divin

Iron chelator

Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells.
PC-60154

ENT1-IN-39

ENT1 inhibitor

ENT1-IN-39 (ENT-1 inhibitor 39) is a potent adenosine transport activity of equilibrative nucleoside transporter I protein (ENT1) with IC50 of 26.9 nM.
PC-70005

Gue-1654

OXE-R inhibitor

Gue-1654 (GUE 1654) is a small-molecule that inhibits Gβγ but not Gα signaling triggered upon activation of Gα(i)-βγ by the chemoattractant receptor OXE-R (Oxoeicosanoid receptor) in both recombinant and human primary cells.
PC-70001

C1632

Lin28 inhibitor

C1632 (Lin28-IN-1632) is a small molecule inhibitor of RNA binding protein Lin28 that blocks the Lin28/let-7 interaction, rescues let-7 processing and function in Lin28-expressing cancer cells.
PC-60090

trans-AUCB

sEH inhibitor

trans-AUCB is a potent, specific and orally bioavailable soluble epoxide hydrolase (sEH) inhibitor with IC50 of 1.3 nM.
PC-60018

RU.521

cGAS inhibitor

RU.521 (RU521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM.
PC-42914

PFK-158

PFKFB3 inhibitor

PFK-158 is the first potent, selective and competitive small molecule inhibitor of PFKFB3 with IC50 of 137 nM, inhibits glycolysis, induces apoptosis and autophagy.
PC-47499

Tat-NR2B9c

PSD-95 inhibitor

Tat-NR2B9c (NA-1) is a neuroprotective agent, exhibits high-affinity binding to the second PDZ domain of PSD-95, inhibits NR2A-NR2C/PSD-95 interactions (IC50=1-10 uM) and nNOS/PSD-95 interaction (IC50=200 nM).
PC-45661

MCB-613

SRC stimulator

MCB-613 is a potent steroid receptor coactivator (SRC1, SRC2 and SRC3) stimulator.
PC-45685

Emixustat hydrochloride

RPE65 inhibitor

Emixustat (ACU-4429) hydrochloride is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
PC-45684

Emixustat

RPE65 inhibitor

Emixustat (ACU-4429) is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.

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