| Cat. No. |
Product Name |
Information |
| PC-72761 |
UbV SP.3
STAMBP inhibitor
|
UbV SP.3 is potent, selective inhibitor of STAMBP isopeptidase activity with KD/IC50 of 60/9.8 nM, with significant preferential binding to STAMBP over STAMBPL1 (250 -fold selectivity). |
| PC-72760 |
UbV SP.1
STAMBP inhibitor
|
UbV SP.1 is potent, selective inhibitor of STAMBP isopeptidase activity with KD of 0.05/0.18 uM for STAMBP/STAMBPL1, respectively. |
| PC-72756 |
TTFB
ZAC antagonist
|
TTFB (ZAC antagonist TTFB) is a selective antagonist (negative allosteric modulator) of Zinc-Activated Channel (ZAC) with IC50 of 3 uM. |
| PC-72746 |
Sari 59-801
|
SaRI 59-801 is an orally effective hypoglycemic compound, decreases blood glucose in several species and to elevate plasma insulin in rats and mice. |
| PC-72738 |
S-Y048
OXE receptor antagonist
|
S-Y048 ((S)-Y048) is a highly potent, selective OXE receptor antagonist, inhibits 5‐oxo‐ETE‐induced calcium mobilization in human neutrophils with pIC50 of 10.8 (20 pM). |
| PC-72667 |
UNC10245131
CIB1 inhibitor
|
UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM. |
| PC-72579 |
SHMT inhibitor SHIN2
SHMT inhibitor
|
SHMT inhibitor SHIN2 ((+) SHIN2) is a potent, selective, mammalian SHMT1/2 inhibitor with antileukemic effect in vivo. |
| PC-72568 |
MBD2 inhibitor APC
MBD2 inhibitor
|
MBD2 inhibitor APC (APC) is a small molecule inhibitor targeting an intrinsically disordered protein region (IDPR) of MBD2 with antimetastatic activity, inhibits DOT-mediated PPI of MBD2, efficiently disrupts MBD2 interaction with p66α with IC50 of 1.03 uM (FRET). |
| PC-72567 |
MBD2 inhibitor ABA
MBD2 inhibitor
|
MBD2 inhibitor ABA (ABA) is a small molecule inhibitor targeting an intrinsically disordered protein region (IDPR) of MBD2 with antimetastatic activity, inhibits DOT-mediated PPI of MBD2, efficiently disrupts MBD2 interaction with p66α with IC50 of 1.4 uM (FRET). |
| PC-72563 |
CC260
PI5P4Kα/β inhibitor
|
CC260 (CC-260) is a potent, selective inhitor of PI5P4Kα/β with Ki of 40/30 nM, respectively. |
| PC-72554 |
PAX inhibitor BG1
PAX inhibitor
|
PAX inhibitor BG1 (PAX-IN-BG1) is a small molecule that attenuate Pax-2 transactivation ability with IC50 of 1.5 uM. |
| PC-72550 |
Compound R80
CTPS1 inhibitor
|
Compound R80 (CTPS1-IN-R80) is a potent, selective inhibitor of CTPS1 (cytidine triphosphate synthase 1) with IC50 of 8.4 nM in RapdFire MS assays, >100-fold selectivity over CTPS2 (IC50=4.3 uM). |
