| Cat. No. |
Product Name |
Information |
| PC-21207 |
Ticlopidine
CD39 inhibitor
|
Ticlopidine (PCR 5332) is an allosteric, noncompetitive inhibitor of CD39 with the IC50 of 81.7 μM, shows antithrombotic effect. |
| PC-21205 |
ARL67156
ecto-ATPase inhibitor
|
ARL67156 (FPL 67156) is a selective inhibitor of ecto-ATPase, ARL67156 is a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. |
| PC-21193 |
Gliotoxin
LTA4 hydrolase inhibitor
|
Gliotoxin (Aspergillin) is a virulence factor of Aspergillus fumigatus, functions as a potent and selective inhibitor of the epoxide hydrolase activity of LTA4 hydrolase (LTA4H), selectively inhibits LTB4 biosynthesis. |
| PC-21176 |
GPR54 antagonist 9l
GPR54 inhibitor
|
GPR54 antagonist 9l is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.7 nM (human GPR54) in receptor binding assays. |
| PC-21175 |
GPR54 antagonist 15a
GPR54 inhibitor
|
GPR54 antagonist 15a is a potent, selective, small molecule antagonist of GPR54 with IC50 of 3.6/15 nM (human/rat GPR54) in receptor binding assays. |
| PC-21149 |
25-Hydroxycholesterol
SREBP-1 inhibitor
|
25-Hydroxycholesterol (25-HC) is a specific sterol regulatory element-binding proteins (SREBP-1) inhibitor, decreases SREBP-1 protein level in cells. |
| PC-21144 |
4-ABAH
MPO inhibitor
|
4-ABAH is a specific irreversible inhibitor of myeloperoxidase (MPO) activity. |
| PC-21100 |
DSHN
NR0B2 agonist
|
DSHN is a small molecule activator of small heterodimer partner (SHP, NR0B2), functions as a transcriptional activator of SHP, inhibits HCC metastasis via SHP-mediated repression of Ccl2 signaling. |
| PC-21096 |
PSB-KD477
GPR18 agonist
|
PSB-KD477 is a potent, selective GPR18 agonist with EC50 of 454 nM, shows no activity against GPR55. |
| PC-21071 |
BDP-13176
Fascin-1 inhibitor
|
BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM. |
| PC-21057 |
C10M
CRP inhibitor
|
C10M is a small molecule inhibitor of C-reactive protein (CRP), inhibits the binding of pCRP to the physiological ligand phosphocholine (PC) with IC50 of 1.5 mM in ELISA assays. |
| PC-21028 |
PIP-199
RMI-MM2 inhibitor
|
PIP-199 is a small-molecule inhibitor of the Fanconi anemia complementation group M-RecQ-mediated genome instability protein (FANCM-RMI) protein-protein interaction, inhibits RMI core complex with Kd of 3.4 uM. |
