| Cat. No. |
Product Name |
Information |
| PC-42281 |
GGTI298
GGTase I inhibitor
|
GGTI298 (GGTI-298) is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor that inhibits the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras (IC50s are 3 and >10 uM respectively). |
| PC-28396 |
α-Fluoromethylhistidine dihydrochloride
Histidine decarboxylase inhibitor
|
alpha-fluoromethylhistidine (α-FMH) is an orally active, irreversible histamine producing enzyme histidine decarboxylase (HDC) inhibitor with IC50 of 1-2 uM for soluble histidine decarboxylase preparations, inhibits histamine synthesis with IC50 of 0.2 uM in intact cell suspensions. |
| PC-28391 |
F-53B
CAS 73606-19-6
|
F-53B (6:2 Cl-PFAES) is a 6:2 chlorinated polyfluorinated ether sulfonate is an alternative to perfluorooctanesulfonate (PFOS) in electroplating industry, significantly inhibits the growth of zebrafish and induces reproductive toxicity. |
| PC-28366 |
MMS-350
Antifibrotic
|
MMS-350 is a DMSO analog and bis-oxetanyl sulfoxide that acts as a radiation protector and mitigator, reduces pulmonary fibrosis induced by different triggers, reduces levels of extracellular matrix proteins, the activation of fibroblasts, and the induction of pro-fibrotic factors. |
| PC-28360 |
XJB-5-131
Antioxidant
|
XJB-5-131 is hemigramicidin-TEMPO conjugate and mitochondria-targeted ROS and electron scavenger, reduces apoptosis and enhances cell survival in mouse embryonic cells in vitro, improves mitochondrial function. |
| PC-28349 |
Herbacetin
Ornithine decarboxylase inhibitor
|
Herbacetin is a naturally occurring flavonoid and potent, specific, allosteric ornithine decarboxylase (ODC) inhibitor, exhibits potent anticancer activity in colon cancer cell lines expressing high levels of ODC. |
| PC-28332 |
PANK-IN-3
PANK3 inhibitor
|
PANK-IN-3 is a high-affinity, selective inhibitor of PANK3 (Pantothenate kinase 3) with Ki of 4.2 nM, 104-fold selective over PanK1β. |
| PC-28331 |
PANK-IN-2
PANK inhibitor
|
PANK-IN-2 is a poten tinhibitor of Pantothenate kinase (PANK) with IC50 of 92 nM for PanK2, 70 nM for PanK1β, and 25 nM for PanK3 respectively in radiochemical enzyme assays. |
| PC-28330 |
PANK-IN-1
PANK3 inhibitor
|
PANK-IN-1 is a potent, pantothenate competitive inhibitor of Pantothenate kinase (PANK) with IC50 of 0.51 uM against PANK3. |
| PC-28291 |
Racemetirosine
Tyrosine hydroxylase inhibitor
|
Racemetirosine (Alpha-methyltyrosine, alphaMT, Alpha-methyl-para-tyrosine) is a competitive small molecule tyrosine hydroxylase inhibitor, inhibits catecholamine biosynthesis, blocks hydroxylation of tyrosine into dihydroxyphenylalanine (DOPA). |
| PC-28249 |
SARM1 inhibitor B339
SARM1 inhibitor
|
SARM1 inhibitor B339 is a potent SARM1 inhibitor with IC50 of 7.215 uM, shows potential in prevention of axonal degeneration. |
| PC-28230 |
NSC 65828 sodium
Angiogenin inhibitor
|
NSC 65828 sodium (NCI-65828) is a small-molecule inhibitor of the ribonucleolytic activity of human angiogenin with Ki of 81 uM; possess antitumor activity in mice. |
