KG-296 | CLOCK/NPAS2 PAS-A inhibitor | Probechem Biochemicals

Chemical Structure : KG-296

KG-296 (KG296)

Catalog No.: PC-26823Not For Human Use, Lab Use Only.

KG-296 is a small molecule ligand that bind to the PAS-A domain of NPAS2 and its paralog CLOCK, binds to CLOCK PAS-A with Kd of 120 uM, specifically binds to CLOCK/NPAS2 PAS-A domains, inhibits DNA binding to CLOCK:BMAL1.

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Biological Activity

Physicochemical Properties

M.Wt	202.21
Formula	C12H10O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(furan-2-ylmethyl)benzoic acid

References

1. Sharma D, et al. bioRxiv [Preprint]. 2026 Apr 14:2026.04.13.718289.

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KG-296 (KG296)

Biological Activity

Physicochemical Properties

References

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