| Cat. No. |
Product Name |
Information |
| PC-42279 |
PF-1355
MPO inhibitor
|
PF-1355 (PF-06281355) is a potent, selective, orally active Myeloperoxidase (MPO) inhibitor with EC50 of 1.47 uM. |
| PC-45669 |
GSK2256294A
sEH inhibitor
|
GSK2256294A is a potent, selective soluble epoxide hydrolase (sEH, EPHX2) inhibitor with IC50 of 27/61/189 pM for recombinant human/rat/mouse sEH, respectively. |
| PC-45486 |
DZ2002
SAHH inhibitor
|
DZ2002 is a potent, reversible type III inhibitor of SAHH (S-adenosyl-L-homocysteine hydrolase) with Ki of 17.9 nM. |
| PC-45053 |
CH-5450
Chymase inhibitor
|
CH-5450 is a potent, peptide-inhibitor of human chymase with Ki of 1 nM. |
| PC-45604 |
PF-06282999
MPO inhibitor
|
PF-06282999 is a potent, highly selective and irreversible inhibitor of myeloperoxidase (MPO) with Kinact/KI of 116000 M-1s-1. |
| PC-45514 |
BoNT-IN-1
BoNT inhibitor
|
BoNT-IN-1 is a potent inhibitor of Botulinum Neurotoxin A (BoNT) Light Chain with IC50 of 0.9 uM. |
| PC-45318 |
Amicarbazone
Photosystem II Inhibitor
|
Amicarbazone (BAY-314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII). |
| PC-45038 |
ISO-1
MIF inhibitor
|
ISO-1 is a potent inhibitor of Migration inhibitory factor (MIF) tautomerase activity with IC50 of 7 uM. |
| PC-42227 |
ML390
DHODH inhibitor
|
ML390 is a potent DHODH inhibitor that causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) AML models (ED50=2 uM). |
| PC-42253 |
HTHQ
Anti-oxidative agent
|
HTHQ is a potent anti-oxidative agent that effectively scavenges t-butyl peroxyl radicals with IC50 of 0.31 mM (ROS inhibition). |
| PC-44643 |
HJC0350
EPAC2 antagonist
|
HJC0350 is a potent and specific EPAC2 antagonist with IC50 of 0.3 uM for competing with 8-NBD-cAMP in binding EPAC2, about 133-fold more potent than cAMP. |
| PC-42382 |
NIH-12848
PI5P4Kγ inhibitor
|
NIH-12848 is a potent and selective PI5P4Kγ inhibitor with IC50 of 1 uM, shows no significant inhibitory activity for PI5P4Kα and PI5P4Kβ (>100 uM). |
