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Chemical Structure : GIBH-130
CAS No.: 1252608-59-5
Catalog No.: PC-60175Not For Human Use, Lab Use Only.
GIBH-130 is a small molecule inhibitor of neuroinflammation, suppresses the proinflammatory cytokine production in LPS-stimulated N9 microglial cells (IC50=3.4 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $258 | In stock | |
| 100 mg | Get quote |
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GIBH-130 is a small molecule inhibitor of neuroinflammation, suppresses the proinflammatory cytokine production in LPS-stimulated N9 microglial cells (IC50=3.4 nM).
GIBH-130 modulates the release of detrimental proinflammatory cytokines.
GIBH-130 exhibits in vivo efficacy of cognitive impairment in both β amyloid-induced and APP/PS1 double transgenic Alzheimer's murine models.
| M.Wt | 360.421 | |
| Formula | C20H20N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
(4-methyl-6-phenylpyridazin-3-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone |
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1. Zhou W, et al. ACS Chem Neurosci. 2016 Nov 16;7(11):1499-1507.
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