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Cat. No. Product Name Information
PC-20889

Lalistat-2

LAL inhibitor

Lalistat-2 (L-stat) is a specific inhibitor of lysosomal acid lipase (LAL) with IC50 of 152 nM, shows no significant activity against pancreatic lipase or lipoprotein lipase.
PC-20883

NCI-41356

CRYAB inhibitor

NCI-41356 is a small molecular inhibitor of αB-crystallin (CRYAB, HSPB5), significantly reducesthe interaction between CRYAB and VEGF165.
PC-20871

NVP-231

CerK inhibitor

NVP-231 (NVP231) is a potent, specific, and reversible ceramide kinase (CerK) inhibitor with IC50 of 12 nM.
PC-20868

Imanixil

LDLR inducer

Imanixil (HOE402) is a small molecule inducer of the LDL receptor (LDLR), HOE402 is a potent cholesterol-lowering compound, inhibits VLDL production.
PC-20866

ARUK200282

PI5P4Kα inhibitor

ARUK200282 is a potent, isoform-selective PI5P4Kα inhibitor with pIC50 of 8.0, selective over PI5P4Kβ and PI5P4Kγ.
PC-20859

LI-2242

IP6K inhibitor

LI-2242 is a potent pan-IP6K inhibitor with IC50 of with IC50 of 31, 42 and 8.1 nM for IP6K1, IP6K2 and IP6K3, respectively.
PC-20846

CC-410

NNMT inhibitor

CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT).
PC-20828

LAG-3 inhibitor SA-15-P

LAG-3 inhibitor

LAG-3 inhibitor SA-15-P is a small molecule dual inhibitor of LAG-3/MHCII and LAG-3/FGL1 interactions with IC50 of 4.21 and 6.52 uM, respectively.
PC-20827

DFTD

eEF-2K inhibitor

DFTD is a time-dependent, reversible and covalent inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K) targeting of Cys-146, DFTD binds to the ATP binding site of eEF-2K.
PC-20821

PKA inhibitor H89

PKA inhibitor

PKA inhibitor H89 (H-89 dihydrochloride) is a potent, selective cAMP-dependent protein kinase A (PKA) inhibitor with IC50 of 48 nM, weakly inhibits PKG, PKC, casein kinases.
PC-20814

Legumain inhibitor 7r

Legumain inhibitor

Legumain inhibitor 7r is a highly potent Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 0.9 nM.
PC-20813

Legumain inhibitor 10t

Legumain inhibitor

Legumain inhibitor 10t is a potent, selective and cellularly active Legumain (asparagine endopeptidase, AEP) inhibitor with IC50 of 71 nM.

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