| Cat. No. |
Product Name |
Information |
| PC-27293 |
FKA-9i
LRPPRC-YBX1-RPN1 inhibitor
|
FKA-9i is a potent broad-spectrum anticancer agent, directly binds to leucine-rich PPR motif-containing protein (LRPPRC), Y-box binding protein 1 (YBX1), and ribophorin I (RPN1) with 7.387 μM, 26.82 μM, and 16.52 μM, respectively, reducing their interactions and stability. |
| PC-27289 |
RUN-89
NRF1 activator
|
RUN-89 is a potent, specific activator of transcription factor nuclear factor erythroid 2-related factor 1 (encoded by NFE2L1, NRF1) with EC50 of 3.1 uM. |
| PC-27287 |
Vosoritide
C-type natriuretic peptide analog, NPR2 agonist
|
Vosoritide (BMN-111) is a biologic analogue of C-type natriuretic peptide (CNP) and a potent stimulator of endochondral ossification, acts to restore chondrogenesis through its binding to natriuretic peptide receptor B (NPR-B, NPR2), resulting in the inhibition of downstream signalling pathways of the overactive FGFR3 gene. |
| PC-27278 |
Catestatin TFA
Catecholamine release inhibitor
|
Catestatin TFA is a potent catecholamine release inhibitory peptide with IC50 of 0.2-0.3 uM, acting as a nicotinic cholinergic antagonist, inhibits nicotinic cholinergic-stimulated catecholamine secretion, signal transduction, and desensitization. |
| PC-27277 |
Catestatin
Catecholamine release inhibitor
|
Catestatin is a potent catecholamine release inhibitory peptide with IC50 of 0.2-0.3 uM, acting as a nicotinic cholinergic antagonist, inhibits nicotinic cholinergic-stimulated catecholamine secretion, signal transduction, and desensitization. |
| PC-27255 |
Dihydroberberine
483-15-8
|
Dihydroberberine (dhBBR) is a berberine derivative that inhibit mitochondrial respiratory complex I, improves whole-body insulin sensitivity through increased AMPK activity, exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways. |
| PC-27253 |
TBC1D2 inhibitor G2
TBC1D2 inhibitor
|
TBC1D2 inhibitor G2 is a small molecule TBC1 domain family member 2 (TBC1D2) inhibitor with SPR KD of 0.4 uM, and IC50 of 80 nM in HCCLM3 cells, induces selective autophagic cell death. |
| PC-27242 |
Elamipretide acetate
Antioxidant tetrapeptide
|
Elamipretide acetate (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types. |
| PC-27237 |
CD73 inhibitor Compound 73
CD73 inhibitor
|
CD73 inhibitor Compound 73 is a potent and selective non-nucleotide small molecule inhibitor of CD73 (ecto-5′-nucleotidase, eN) with IC50 of 12 nM. |
| PC-27230 |
MI-1148
Furin inhibitor
|
MI-1148 is a potent, peptidomimetic furin inhibitor with Ki of 5.5 pM, has significant protective effect against anthrax and diphtheria toxin, shows potent anti-infectious activity against H5N1 and H7N1 avian influenza viruses, West Nile and Dengue virus. |
| PC-27211 |
MEISi-3
MEIS2 inhibitor
|
MEISi-3 is a small molecule MEIS2 inhibitor targeting MEIS2 proteins effectively along with MEIS1, exhibits potent growth inhibition with IC50 of 0.1 μM in SK-BR-3 cells. |
| PC-27204 |
Semax
Neuroactive peptide
|
Semax is a BBB-penetrable, synthetic peptide analog of Adrenocorticotropic hormone (ACTH) (4-10), can form stable complexes with Cu2+, has immunomodulatory, nootropic and neuroprotective activities. |
