| Cat. No. |
Product Name |
Information |
| PC-26826 |
Cetrimonium bromide
EBNA1 inhibitor
|
Cetrimonium bromide (CetB) is a specific small-molecule inhibitor of Epstein-Barr virus (EBV) latently infected cancer cells, reduces EBNA1 protein stability, activates G1 arrest and early apoptosis of EBV-latently infected cells without viral lytic reactivation, modulates canonical and non-canonical TGF-β signaling pathways, inhibits cancer cell migration and invasion. |
| PC-26823 |
KG-296
CLOCK/NPAS2 PAS-A inhibitor
|
KG-296 is a small molecule ligand that bind to the PAS-A domain of NPAS2 and its paralog CLOCK, binds to CLOCK PAS-A with Kd of 120 uM, specifically binds to CLOCK/NPAS2 PAS-A domains, inhibits DNA binding to CLOCK:BMAL1. |
| PC-26819 |
Myricoside
B4GALT3 inhibitor
|
Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor. |
| PC-26815 |
Acarbose
alpha-glucosidase inhibitor
|
Acarbose (BAY g 5421) is an antihyperglycemic agent and orally active alpha-glucosidase (α-glucosidase) inhibitor with IC50 of 11 nM, potentiates the hypoglycemic effects of sulfonylureas or insulin. |
| PC-26814 |
HMGCS1 inhibitor CNP7
HMGCS1 inhibitor
|
CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation. |
| PC-26812 |
BI-0115
LOX-1 inhibitor
|
BI-0115 is a selective small molecule inhibitor of lectin-like oxidized LDL receptor-1 (LOX-1) with IC50 of 5.4 uM, blocks cellular uptake of oxidized low-density lipoproteins (oxLDL). |
| PC-26802 |
CNT2198
DES1 inhibitor
|
CNT2198 is a potent, selective dihydroceramide desaturase 1 (DES1) inhibitor, lowers renal ceramides, increases dihydroceramides, and shifts complex sphingolipid saturation without evidence of off-target effects. |
| PC-26799 |
XM462
Dihydroceramide desaturase inhibitor
|
XM462 is a small molecule inhibitor of dihydroceramide desaturase (Des1) with IC50 of 8.2 uM and Ki of 2 uM, inhibits sphingolipid synthesis, triggers autophagy and reduces amyloid secretion by neurons. |
| PC-26798 |
Des 1 inhibitor GT11
Des1 inhibitor
|
Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280) is a competitive inhibitor of dihydroceramide desaturase with Ki of 6 uM, induces Des1 inhibition in rat liver microsomes with IC50 of 20 uM. |
| PC-26797 |
PR280
Des1 inhibitor
|
PR280 is a potent small molecule inhibitor of dihydroceramide desaturase 1 (Des1) with IC50 of 700 nM. |
| PC-26781 |
C26-Ceramide
121459-09-4
|
C26 Ceramide is a lipid featuring two hydrophobic tails, one saturated and the other unsaturated, can be used in developing lipid nanoparticles or liposomes. |
| PC-26779 |
(Z)-Ligustilide
CAS 81944-09-4
|
(Z)-Ligustilide is an orally active natural compound from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD). |
