| Cat. No. |
Product Name |
Information |
| PC-27531 |
HA-CD44 inhibitor 1
CD44 inhibitor
|
HA-CD44 inhibitor 1 is a potential Hyaluronic acid (HA)-CD44 interaction inhibitor, effectively blocks HA-CD44 binding, shows antiproliferative activity against MDA-MB-231 cells with EC50 of 1.77 uM. |
| PC-27529 |
Polyphyllin VI
CAS 55916-51-3
|
Polyphyllin VI (PP-VI, PPVI) is a steroidal saponin isolated from Paris polyphylla with broad and strong anticancer effect and anti-metastatic activity, increases expression of Rell2 (Receptor expressed in lymphoid tissue (RELT)-like 2) and decreases level of miR-18a in 4T1 and MDA-MB-231 cells. |
| PC-27527 |
Rbin-2
Midasin inhibitor
|
Rbin-2 is a potent, reversible and selective inhibitor of AAA+ protein Midasin (Mdn1), inhibits eukaryotic ribosome biogenesis. |
| PC-27524 |
SAIT-PDZ-5179
GIPC1 inhibitor
|
SAIT-PDZ-5179 is a small molecule inhibitor of GAIP-interacting protein C terminus 1 (GIPC1), selectively target the PDZ domain of GIPC1 with ITC KD of 943 nM. |
| PC-27518 |
Zumododstat
DHODH inhibitor
|
Zumododstat is a potent, selective inhibitor of dihydro-orotate dehydrogenase (DHODH). |
| PC-27506 |
JXL020
MPC inhibitor
|
JXL020 is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 16.6 nM. |
| PC-27463 |
Alpha-D-Glucose-1-phosphate disodium
CAS 56401-20-8
|
α-D-Glucose-1-phosphate disodium (Fosdemannose) is a derivative of D-glucose as a starting material for glucuronic acid synthesis, also is a cytostatic compound, antibiotic and immunosuppressant. |
| PC-27438 |
Uniconazole
ABA catabolism inhibitor
|
Uniconazole is a plant growth retardant and potent inhibitor of abscisic acid (ABA) catabolism in Arabidopsis with IC50 of 68 nM for ABA 8’-hydroxylase, also is a potent competitive inhibitor of CYP707A3 activity with Ki of 8 nM, inhibits gibberellin biosynthesis. |
| PC-27435 |
DIBDO
GSDMD agonist
|
DIBDO is a small molecule gasdermin D (GSDMD) agonist, directly activates GSDMD bypassing Caspase-3, blocks Caspase-3 activation and induces GSDMD‐mediated pyroptosis in tumor cells. |
| PC-27433 |
Retro-2.2
Retrograde transport inhibitor
|
Retro-2.2 is a derivative of cellular retrograde transport inhibitor Retro-2, inhibits human respiratory syncytial virus (hRSV) replication in cell culture and impairs the ability of hRSV to form syncytia. |
| PC-27432 |
Retro-2 cycl
Retrograde transport inhibitor
|
Retro-2(cycl) (Retro-2 cycl) is a small molecule inhibitor of host retrograde trafficking, inhibits ricin and Shiga-like toxins (SLTs), inhibits infection by JCPyV, BKPyV, and simian virus 40 (SV40). |
| PC-27431 |
(S)-Retro-2.1
Retrograde transport inhibitor
|
Retro-2.1a ((S)-Retro-2.1) is a potent molecule to counteract the cytotoxic potential of ricin and Shiga toxin with EC50 of 23 nM and 54 nM, respectively, blocking retrograde transport and intracellular retrograde trafficking. |
