ABCA1 inducer 39

Chemical Structure : ABCA1 inducer 39

Catalog No.: PC-22962Not For Human Use, Lab Use Only.

ABCA1 inducer 39 is a nonlipogenic ABCA1-inducer (NLAI) with EC50 of 0.1 uM, increases ABCA1 expression, enhances APOE lipidation, and reverses multiple AD phenotypes, without increasing triglycerides (TG).

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Biological Activity

Physicochemical Properties

M.Wt	587.48
Formula	C24H24Cl2N2O7S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 3-chloro-5-(5-chloro-3-(N-(4-ethoxy-3-methoxyphenyl)-N-methylsulfamoyl)thiophene-2-carboxamido)benzoate

References

1. Ganga Reddy Velma, Journal of Medicinal Chemistry August 27, 2024

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ABCA1 inducer 39

Biological Activity

Physicochemical Properties

References

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