| Cat. No. |
Product Name |
Information |
| PC-23351 |
MASTL inhibitor 16
MASTL inhibitor
|
MASTL inhibitor 16 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of 0.12 nM, cellular pENSA IC50 of 2.8 nM in MDA-MB-231 cells. |
| PC-23350 |
MASTL inhibitor 15
MASTL inhibitor
|
MASTL inhibitor 15 is a potent, highly selective inhibitor of microtubule-associated serine/threonine kinase-like (MASTL, Greatwall) with Ki of <0.03 nM, cellular pENSA IC50 of 1.1 nM in MDA-MB-231 cells. |
| PC-23327 |
8-prenylnaringenin
CDCP1 inhibitor
|
8-prenylnaringenin (8PN) is a prenylflavonoid isolated from hop cones Humulus lupulus with cytotoxicity, is a small molecule inhibitor of CUB domain‐containing protein 1 (CDCP1)and reduces CDCP1 protein levels in cancer cells. |
| PC-23326 |
HPA-12
CERT inhibitor
|
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis. |
| PC-23324 |
SIM1
Stomatal opening inhibitor
|
SIM1 is a small molecule inhibitor of stomatal opening, inhibits the light induced stomatal opening of Arabidopsis with IC50 of 44.9 uM, affects stomatal aperture. |
| PC-23308 |
AK-778-XXMU
ID2 inhibitor
|
AK-778-XXMU is a small molecule inhibitor of protein ID2 (inhibitor of DNA binding 2) with SPR KD value of 129 nM. |
| PC-23287 |
HKi6
HEG1-KRIT1 inhibitor
|
HKi6 is a specific small-molecule HEG1-KRIT1 inhibitor (IC50=1.5 uM) by competing orthosterically with HEG1 for binding to the KRIT1 FERM domain, elevates KLF4 and KLF2 gene expression and increases Akt phosphorylation. |
| PC-23282 |
Malabaricone C
Sphingomyelin synthase inhibitor
|
Malabaricone C is a natural sphingomyelin synthase (SMS) inhibitor with IC50 values of 3 uM and 1.5 μM for SMS1 and SMS2, respectively. |
| PC-23220 |
VPS18 inhibitor RDN
VPS18 inhibitor
|
VPS18 inhibitor RDN is a specific lysosomotropic agent that targeting vacuole protein sorting 18 (VPS18), binds to the RING domain of VPS18, leading to disruption of the VPS-C core complex and lysosomal function. |
| PC-23217 |
Steroid sulfatase inhibitor DU-14
Steroid sulfatase inhibitor
|
Steroid sulfatase inhibitor DU-14 is a hihly potent steroid sulfatase inhibitor with IC50 of 55.8 nM, inhibits inhibits the MCF-7 cell proliferation with IC50 of 38.7 nM. |
| PC-23192 |
Swainsonine
Golgi α-mannosidase inhibitor
|
Swainsonine (Tridolgosir) is a natural product indolizidine alkaloid and an inhibitor of the human Golgi α-mannosidase, hGMII (MAN2A1), induces apoptosis and cell cycle arrest at G2/M phase, shows anti-tumor activity. |
| PC-23190 |
NB-115
FOXM1 inhibitor
|
NB-115 is a small molecule FOXM1 inhibitor with Ki of 40 nM and IC50 of 216 nM, suppresses TNBC progression and tumor metastasis. |
