| Cat. No. |
Product Name |
Information |
| PC-49387 |
Meprin α inhibitor 10d
Meprin α inhibitor
|
Meprin α inhibitor 10d (Compound 10d) is a potent specific Meprin α inhibitor with IC50 of 160 nM, less potent for meprin β (IC50=2,950 nM). |
| PC-49386 |
S9-A13
SLC26A9 inhibitor
|
S9-A13 is a highly potent and specific inhibitor of SLC26A9, potently inhibits SLC26A9-mediated Cl−/I− and Cl−/SCN− exchange activities with IC50 of 90.9 and 171.5 nM, respectively. |
| PC-49384 |
DKC1125
KITENIN inhibitor
|
DKC1125 is a small molecule KSRP-binding compound that specifically inhibits the oncogenic KITENIN complex, suppresses distant metastasis of colorectal cancer (CRC). |
| PC-49381 |
Aldometanib
Aldolase inhibitor
|
Aldometanib (LXY-05-029) is a selective small molecule inhibitor of aldolase (ALDOA) with IC50 of 50 uM in in vitro enzymatic assays, Aldometanib (5 nM) is sufficient to activate AMPK inside cells. |
| PC-49379 |
BDK inhibitor BT3
BDK inhibitor
|
BDK inhibitor BT3 is a small molecule allosteric inhibitor of BCKDC kinase (BDK). |
| PC-49378 |
BDK inhibitor BT2
BDK inhibitor
|
BDK inhibitor BT2 is a small molecule allosteric inhibitor of BCKDC kinase (BDK, branched-chain ketoacid dehydrogenase kinase) with IC50 of 3.19 uM. |
| PC-49370 |
GCN2 inhibitor 39
GCN2 inhibitor
|
GCN2 inhibitor 39 is a highly potent and selective, orally active inhibitor of general control nonderepressible 2 (GCN2) with IC50 of 5 nM. |
| PC-49359 |
PXS-4787
pan-LOX inhibitor
|
PXS-4748 (PXS4748) is a potent, selective and irreversible pan-lysyl oxidase (pan-LOX) inhibitor with IC50 of 2.0 uM and 3.2/0.6/1.4/0.2 uM for bovine (aorta) LOX and rh LOXL1/2/3/4, respectively. |
| PC-49358 |
PXS-6302
pan-LOX inhibitor
|
PXS-6302 (PXS6302) is a potent, irreversible pan-lysyl oxidase (pan-LOX) inhibitor with IC50 of 3.7 uM and 3.4/0.4/1.5/0.3 uM for bovine (aorta) LOX and rh LOXL1/2/3/4, respectively. |
| PC-49336 |
JBSNF-000028
NNMT inhibitor
|
JBSNF-000028 (JBSNF000028) is a potent, selective, orally bioavailable substrate-analog inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 34 nM, 190 and 210 nM against human, monkey and mouse NNMT, respectively. |
| PC-49332 |
4-Sulfocalix[8]arene hydrate
AIM2 inhibitor
|
4-Sulfonic calix[8]arene is a potent AIM2 inflammasome inhibitor that work by binding competitively to the DNA binding site, dose dependently inhibits AIM2-dependent cell death and IL-1β release. |
| PC-49331 |
4-Sulfocalix[6]arene hydrate
AIM2 inhibitor
|
4-Sulfonic calix[6]arene is a potent AIM2 inflammasome inhibitor that work by binding competitively to the DNA binding site, dose dependently inhibits AIM2-dependent cell death and IL-1β release. |
